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Daisy

Pomsky

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Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Genetic Stats

Predicted Adult Weight

31 lbs

Genetic Age
20 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Siberian Husky
Pomeranian

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Health Summary

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OVP Daisy inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Degenerative Myelopathy, DM

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OVP Daisy inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), OVP Daisy is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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OVP Daisy inherited both copies of the variant we tested

Why is this important to your vet?

OVP Daisy has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in OVP Daisy's ALT activity above their current, healthy, ALT activity. As an increase above OVP Daisy’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Methemoglobinemia (CYB5R3)

Identified in Pomeranians

Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through OVP Daisy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A405

Map

A1b

Daisy’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A405

Daisy’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that OVP Daisy inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since OVP Daisy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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