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“Mysti”
Cribbs Mystic Magic

Labrador Retriever

No bio has been provided yet

Place of Birth
Eustis, FL, USA
Current Location
Brooksville, FL, USA

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Registration

AKC: SR91734301

Genetic Breed Result

Learn how it’s done

Labrador Retriever

Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
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Genetic Stats


Predicted Adult Weight
Genetic Age
42 human years Learn More
Based on the date of birth provided

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Health Summary

Mysti is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Progressive Retinal Atrophy, prcd

Mysti inherited both copies of the variant we tested

How to interpret this result

Mysti has two copies of a mutated allele at PRCD and is at risk for developing PRA. Remember that PRA is a subtle disease with a variable age of onset, and that the gold standard for diagnosing PRA is a thorough ophthalmologic exam and specialized tests to evaluate retinal function. Please consult with your veterinarian to develop a diagnostic and monitoring plan for Mysti.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

Hereditary Nasal Parakeratosis

Mysti inherited one copy of the variant we tested

What does this result mean?

This result should not impact Mysti’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring.

What is Hereditary Nasal Parakeratosis?

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog.

Breed-Relevant Genetic Conditions

Congenital Macrothrombocytopenia (TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)

Identified in Labrador Retrievers

Canine Elliptocytosis (SPTB Exon 30)

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency (PKLR Exon 7 Labrador Variant)

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2 (TTC8)

Identified in Labrador Retrievers

Progressive Retinal Atrophy - crd4/cord1 (RPGRIP1)

Identified in Labrador Retrievers

Day Blindness (CNGA3 Exon 7 Labrador Retriever Variant)

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD (CHST6)

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Labrador Retrievers

Alexander Disease (GFAP)

Identified in Labrador Retrievers

Narcolepsy (HCRTR2 Intron 6)

Identified in Labrador Retrievers

Exercise-Induced Collapse (DNM1)

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy (MTM1, Labrador Variant)

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome (COLQ)

Identified in Labrador Retrievers

Oculoskeletal Dysplasia 1 (COL9A3, Labrador Retriever)

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2 (COL11A2)

Identified in Labrador Retrievers

Additional Genetic Conditions


Clinical Tools

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a mostly solid black or brown coat (KBKB)
A Locus (ASIP)
Not expressed (atat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (DD)
B Locus (TYRP1)
Brown hair and skin (bb)
Saddle Tan (RALY)
Not expressed (NI)
M Locus (PMEL)
No merle alleles (mm)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely heavy/seasonal shedding (CC)
Coat Texture (KRT71)
Likely straight coat (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Hairlessness (SGK3)
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Back Muscling & Bulk, Large Breed (ACSL4)
Likely normal muscling (CC)
Body Size

Body Size

Body Size (IGF1)
Intermediate (NI)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Intermediate (TA)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Mysti’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A400

Map

A1a

Cribbs Mystic Magic’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A400

Cribbs Mystic Magic’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Mysti inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Mysti is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.