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“Prince”
Cox

Soft Coated Wheaten Terrier

“Dependable stud”

This dog has been viewed and been given 7 wags

Registration

American Kennel Club (AKC): RN26508

Genetic Breed Result

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Soft Coated Wheaten Terrier

Soft Coated Wheaten Terriers are happy-go-lucky dogs with a wonderfully fluffy coat. These medium sized dogs were bred in Ireland to do everything from herding to hunting to even fishing. Today, they are primarily companion dogs due to their devote love of people.

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Health Summary

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Prince has one variant that you should let your vet know about.

ALT Activity

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Prince inherited one copy of the variant we tested

Why is this important to your vet?

Prince has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Prince has this genotype, as ALT is often used as an indicator of liver health and Prince is likely to have a lower than average resting ALT activity. As such, an increase in Prince’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Protein Losing Nephropathy, PLN (NPHS1)

Identified in Soft Coated Wheaten Terriers

Degenerative Myelopathy, DM (SOD1A)

Identified in Soft Coated Wheaten Terriers

Paroxysmal Dyskinesia, PxD (PIGN)

Identified in Soft Coated Wheaten Terriers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Prince’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A26a/305

Map

A1d

Cox’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A26a/305

Cox’s Haplotype

Part of the large A1d haplogroup, we have not yet detected this haplotype in any of our village dogs. Among the 6 breeds we see it in, it appears most frequently in Newfoundlands, Cavalier King Charles Spaniels, and soft coated Wheaten Terriers.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Prince’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

H3

Map

A2b

Cox’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

H3

Cox’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Cavalier King Charles Spaniels, Brittanys, Soft Coated Wheaten Terriers, and village dogs in Lebanon.

A2b is found in the Daschund breed.

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