What is Embark?

Cole

Mixed Breed

“My hobbies insist of playing frisbee, Eating pinecones, swimming, but I HATE baths. I also love bring Mom dead gophers, Watching her scream and jump is priceless! I LOVE being outside, but I don't mind being inside. When Anyone touches me I get jumpy. Well except my girl friend Mylie the psycho cat who lives in the back yard. I also love to go anywhere my mom goes. Did I mention I love to oink like a pig, chase lasers like a cat. Mom was very surprised I was not part pig or part cat. 😂”

This dog has been viewed 559 times and been given 0 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

36.0% Australian Shepherd
33.5% Labrador Retriever
16.5% Australian Cattle Dog
14.0% Golden Retriever
Australian Shepherd Australian Shepherd
Australian Shepherds are an energetic mid-sized breed that make the perfect companion.
Learn More
Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
Learn More
Australian Cattle Dog Australian Cattle Dog
A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.
Learn More
Golden Retriever Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
Learn More
Start a conversation! Log in to send a direct message to this dog’s owner.

Genetic Stats

Wolfiness: 1.1 % MEDIUM Learn More
Predicted Adult Weight: 74 lbs Learn More
Genetic Age: 45 human years Learn More

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Cole’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Australian Shepherd
Labrador Retriever
Australian Cattle Dog
Golden Retriever

Explore:

Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Labrador Retriever mix Australian Shepherd mix Australian Cattle Dog / Labrador Retriever mix Labrador Retriever Australian Shepherd Australian Shepherd / Golden Retriever mix Australian Cattle Dog Labrador Retriever mix Labrador Retriever Labrador Retriever Australian Shepherd Australian Shepherd Australian Shepherd Golden Retriever
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Cole’s breed mix, but this family tree may not be the only possible one.

Explore:

Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

1
AT RISK
0
CARRIER
163
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Cole has two normal alleles at ALT.

At Risk for 1 genetic condition

Cole has tested positive for 1 of the genetic diseases that Embark tests for.
What does At Risk mean?

Testing positive is predictive of your dog being affected by this condition, but it is not a final diagnosis nor does it predict when symptoms may occur or the severity of a condition in your dog.

Please consult with your veterinarian to determine the best course of action.

Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Not A Carrier

Good news! Cole is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Cole tested clear for 34 genetic conditions that are common in his breed mix.
Condition List

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Cole.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A largely benign disease of red blood cell shape, elliptocytosis rarely causes symptoms. Upon examinatino of a blood smear, however, affected dogs have elongated, oval or…

Seen in Labrador Retrievers, but not Cole.

Cyclic Neutropenia, Gray Collie Syndrome
(AP3B1 Exon 20)
Blood

This is a disease of neutrophil production where the number of circulating neutrophils drops precipitously, leaving dogs prone to bacterial infections, and then slowly re…

Seen in Australian Shepherds, but not Cole.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Cole.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Australian Shepherds, Labrador Retrievers, Australian Cattle Dogs, Golden Retrievers, but not Cole.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, Golden Retrievers, but not Cole.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Cole.

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Australian Shepherds, but not Cole.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Cole.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a nonprogressive retinal disease that, in rare cases, can lead to vision loss. All known mutations lie in the BEST1 gene and are inherited in an autosomal recessi…

Seen in Australian Shepherds, but not Cole.

Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts
(HSF4 Exon 9 Shepherd Variant)
Eyes

One of the leading causes of blindness in dogs (and humans!), cataracts are a progressive disease of the lens that causes functional blindness, but can be surgically corr…

Seen in Australian Shepherds, but not Cole.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Australian Cattle Dogs, but not Cole.

Macular Corneal Dystrophy (MCD)
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Cole.

Cystinuria Type II-A
(SLC3A1)
Kidney and Bladder

A disease of cystine accumulation, affected dogs are prone to developing cystine kidney and bladder stones, which if caught early can be managed with dietary changes, inc…

Seen in Australian Cattle Dogs, but not Cole.

Neuronal Ceroid Lipofuscinosis 1
(CLN5 Exon 4 Variant 1)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Cole.

Neuronal Ceroid Lipofuscinosis 6
(CLN6 Exon 7)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Shepherds, but not Cole.

Neuronal Ceroid Lipofuscinosis
(CLN8)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Shepherds, Australian Cattle Dogs, but not Cole.

Neuronal Ceroid Lipofuscinosis
(CLN5 Exon 4 Variant 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Golden Retrievers, but not Cole.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Australian Shepherds, Labrador Retrievers, Australian Cattle Dogs, Golden Retrievers, but not Cole.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Cole.

Muscular Dystrophy
Muscular Dystrophy (DMD Golden Retriever Variant)
Muscular

Characterized by non-painful muscle weakness and wasting, early diagnosis and supportive treatment can slow the pace of this progressive muscle disease. All known mutatio…

Seen in Golden Retrievers, but not Cole.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as one month, the …

Seen in Labrador Retrievers, but not Cole.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Labrador Retrievers, but not Cole.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Australian Cattle Dogs, but not Cole.

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Cole.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in Australian Shepherds, Labrador Retrievers, Australian Cattle Dogs, Golden Retrievers, but not Cole.

Congenital Myasthenic Syndrome
(COLQ)
Neuro-muscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Cole.

Dystrophic Epidermolysis Bullosa
(COL7A1)
Skin & Connective Tissues

This skin disorder gives affected dogs skin that stretches and tears easily; affected dogs must be monitored closely and treated promptly for any injuries. It arises from…

Seen in Golden Retrievers, but not Cole.

Ichthyosis
(PNPLA1)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Seen in Golden Retrievers, but not Cole.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Cole.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Cole.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A1)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Golden Retrievers, but not Cole.

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Cole.

Craniomandibular Osteopathy (CMO)
(SLC37A2)
Skeletal

A noncancerous, proliferative bone disease that commonly affects the lower jaw and tympanic bullae, CMO is best known in the West Highland White Terrier, Scottish Terrier…

Seen in Australian Shepherds, but not Cole.

Other Conditions: Clear of 129

Cole is clear of 129 other genetic diseases that Embark tests for.

Explore:

Family tree

Traits

Maternal Haplotype

Paternal Haplotype

Jump to:

Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EmE
K Locus (Dominant Black)
kyky
A Locus (Agouti, Sable)
atat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GT
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
AC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

Explore:

Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Cole’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Cole’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Cole’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Explore:

Family tree

Health

Traits

Paternal Haplotype

Through Cole’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.10

Map

A2b

Cole’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.10

Cole’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Labrador Retrievers, Rottweilers, Curly-Coated Retrievers, Dandie Dinmont Terriers, and village dogs throughout the world.

Some other Embark dogs with this haplotype:

A2b is found in the Daschund breed.

Explore:

Family tree

Health

Traits

Maternal Haplotype