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Chloe

Mixed Ancestry

“Chloe came to the U.S. from Puerto Rico, where she had been an "owner turn-in." A Northern VA rescue group sponsored her trip & she arrived in the states Aug '16 ...pregnant! After weaning her 6 pups, all were then adopted out, & then it was her turn! I spotted her on Petfinder, called to see about meeting her, & now, ~4 months later, she's all settled into her new (though the D.C. climate is much colder than Puerto Rico!) life!”

Place of Birth

San Juan, San Juan, Puerto Rico

Current Location

McLean, Virginia, USA

From

Fairfax, Virginia, USA

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Genetic Breed Result

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Shih Tzu

This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Dogs Like Chloe

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Discover dogs who share a similar breed mix to Chloe. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Shih Tzu
Beagle
Cocker Spaniel

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Here’s what Chloe’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Chloe’s breed mix.
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Health Summary

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Chloe has one variant that you should let your vet know about.

ALT Activity

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Chloe inherited one copy of the variant we tested

Why is this important to your vet?

Chloe has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Chloe has this genotype, as ALT is often used as an indicator of liver health and Chloe is likely to have a lower than average resting ALT activity. As such, an increase in Chloe’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency

Identified in Beagles

Prekallikrein Deficiency

Identified in Shih Tzus

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, prcd

Identified in Cocker Spaniels

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Primary Open Angle Glaucoma

Identified in Beagles

Familial Nephropathy

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Intervertebral Disc Disease (Type I)

Identified in Beagles, Cocker Spaniels, and more

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Chloe’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B43

Map

B1

Chloe’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B43

Chloe’s Haplotype

Part of the large B1 haplogroup, we have spotted this haplotype in Havanese, Cocker Spaniels, and village dogs in Mexico.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Chloe inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Chloe is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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