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Chief

Mixed Ancestry

  • Chief, a German Shepherd Dog and Labrador Retriever mix tested with EmbarkVet.com Chief, a German Shepherd Dog and Labrador Retriever mix tested with EmbarkVet.com
    Camping 2015 paitiently waiting for his bologna sandwich

“In his younger years he loved to ride the jetski.”

Place of Birth

Fenton, Missouri, USA

Current Location

Arnold, Missouri, USA

From

Fenton, Missouri, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Norwegian Elkhound

The Norwegian Elkhound was the main companion of the Vikings. These guys have been used in almost every role imaginable for a dog. In modern times, they are primarily companion dogs, but they are still used for hunting and herding.

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Maltese

Maltese dogs are confident and friendly toy dogs, that can be high maintenance but boast a beautiful white silky coat.

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Chinese Shar-Pei

Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Dogs Like Chief

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Discover dogs who share a similar breed mix to Chief. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
German Shepherd Dog
Labrador Retriever
Rottweiler
Norwegian Elkhound
Maltese
Chinese Shar-Pei
Boxer
Supermutt

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Here’s what Chief’s family tree may have looked like.
Chief
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Rottweiler / Boxer mix Maltese / Chinese Shar-Pei mix German Shepherd Dog mix Labrador Retriever / Norwegian Elkhound mix Rottweiler Boxer mix Maltese mix Chinese Shar-Pei mix German Shepherd Dog German Shepherd Dog mix Labrador Retriever Norwegian Elkhound
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Chief’s breed mix.
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Health Summary

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Chief is at increased risk for three genetic health conditions.

And inherited one variant that you should learn more about.

Multiple Drug Sensitivity

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Chief inherited one copy of the variant we tested

How to interpret this result

Chief has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While he may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on Chief. Please inform your veterinarian that Chief carries this variant; it is essential that they know this information before prescribing drugs.

What is Multiple Drug Sensitivity?

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.

Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever

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Chief inherited one copy of the variant we tested

How to interpret this result

Chief has one copy of a variant in the MTBP gene and is considered at risk for developing SPAID. More commonly known as Familial Shar-Pei Fever, this condition causes recurrent high fevers and joint swelling and pain. Some Shar-Peis will also develop an inappropriate accumulation of protein in the liver and kidneys. This variant likely has an incomplete dominant inheritance in the Shar-Pei, meaning that Shar-Peis with one copy of the variant are at lower risk when compared to dogs with two copies of the variant, but at greater risk than dogs with no copies of the variant. Please consult with your veterinarian to discuss further diagnostic, treatment, and monitoring options for Chief.

What is Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever?

More commonly known as Familial Shar-Pei Fever, this autoinflammatory condition causes recurrent high fevers, joint swelling and pain, and overall malaise. Some Shar-Peis will also develop amyloidosis, an inappropriate accumulation of an abnormal protein, amyloid, in the liver and kidneys.

Intervertebral Disc Disease (Type I)

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Chief inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is likely to increase the risk that Chief will develop this disease.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Chief have not yet been the focus of research studies, our data indicates that Chief is likely to be at increased risk.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Degenerative Myelopathy, DM

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Chief inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Chief’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Chief is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Hemophilia A

Identified in Boxers

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, prcd

Identified in Norwegian Elkhounds and Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Day Blindness

Identified in German Shepherd Dogs

Day Blindness

Identified in Labrador Retrievers

Primary Open Angle Glaucoma

Identified in Norwegian Elkhounds

Primary Open Angle Glaucoma and Primary Lens Luxation

Identified in Chinese Shar-Peis

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs and Labrador Retrievers

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Glycogen Storage Disease Type IA, Von Gierke Disease, GSD IA

Identified in Malteses

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Alexander Disease

Identified in Labrador Retrievers

Narcolepsy

Identified in Labrador Retrievers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Chondrodystrophy

Identified in Norwegian Elkhounds

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Chief’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1/13

Map

B1

Chief’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1/13

Chief’s Haplotype

Part of the large B1 haplogroup, this common haplotype occurs in Shih Tzus, Tibetan Spaniels, Maltese, and village dogs throughout the world including Central and South America, South Asia, and the South Pacific.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Chief’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.2

Map

A2b

Chief’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.2

Chief’s Haplotype

Part of the A2b haplogroup, this haplotype has been found in Chinese Shar-pei and village dogs in Papua New Guinea.

A2b is found in the Daschund breed.

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