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“Riot”
GCH. CH. Guichon's Knockout Quiet Riot

Chihuahua

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“CHIC # 147008”

Place of Birth

Purcellville, VA, USA

Current Location

Bayfield, CO, USA

From

Purcellville, VA, USA

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Registration

American Kennel Club (AKC): TS41115502

Genetic Breed Result

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Genetic Stats

Predicted Adult Weight

5 lbs

Genetic Age
32 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 3/18/2022 changed name from "GCH CH Guichon's Knockout Quiet Riot" to "GCH. CH. Guichon's Knockout Quiet Riot"
  • On 9/9/2021 changed name from "CH Guichon's Knockout Quiet Riot" to "GCH CH Guichon's Knockout Quiet Riot"

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Health Summary

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Riot inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Riot inherited one copy of the variant we tested

What does this result mean?

This result should not impact Riot’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

ALT Activity

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Riot inherited one copy of the variant we tested

Why is this important to your vet?

Riot has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Riot has this genotype, as ALT is often used as an indicator of liver health and Riot is likely to have a lower than average resting ALT activity. As such, an increase in Riot’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis 7, NCL 7 (MFSD8, Chihuahua and Chinese Crested Variant)

Identified in Chihuahuas

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10)

Identified in Chihuahuas

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Chihuahuas

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Riot’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C18

Map

C2

GCH. CH. Guichon's Knockout Quiet Riot’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C18

GCH. CH. Guichon's Knockout Quiet Riot’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most commonly in Nova Scotia Duck Tolling Retrievers, Pomeranians, and Chihuahuas.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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Through Riot’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.39/57

Map

A1a

GCH. CH. Guichon's Knockout Quiet Riot’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.39/57

GCH. CH. Guichon's Knockout Quiet Riot’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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