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Cheyenne

“Cheyenne will be 12 years old in March 2019. She was sold with an inaccurate breed label so I've decided to find out what she really is.”

Place of Birth

Oklahoma, USA

Current Location

Oklahoma, USA

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Genetic Breed Result

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Gray Wolf

The Gray Wolf is the largest of all the wolf species. These are pack animals that are tactical hunters. While they are wild animals, wolves are still able to breed with dogs.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Samoyed

A working breed, the Samoyed can be strong-willed at times, but above all they remain friendly, gentle, and devoted family dogs. The Samoyed was originally bred to hunt, haul sledges, and herd reindeer. Among the breed’s duties: pack hiking, tracking, and warming their owners by sleeping on top of them at night.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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DNA Breed Origins

Breed colors:
German Shepherd Dog
Alaskan Malamute
Gray Wolf
Siberian Husky
Samoyed
Rottweiler

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Health Summary

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Cheyenne has one variant that you should let your vet know about.

ALT Activity

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Cheyenne inherited one copy of the variant we tested

Why is this important to your vet?

Cheyenne has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Cheyenne has this genotype, as ALT is often used as an indicator of liver health and Cheyenne is likely to have a lower than average resting ALT activity. As such, an increase in Cheyenne’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Alaskan Malamutes

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

X-Linked Progressive Retinal Atrophy 1, XL-PRA1

Identified in Samoyeds and Siberian Huskies

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

X-Linked Hereditary Nephropathy, XLHN

Identified in Samoyeds

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs and Siberian Huskies

Alaskan Malamute Polyneuropathy, AMPN

Identified in Alaskan Malamutes

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Cheyenne’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Cheyenne’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Cheyenne’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Cheyenne inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Cheyenne is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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