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“Jethro”
Charm City's Black Gold

Pomeranian

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Health Summary

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Jethro inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Methemoglobinemia

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Jethro inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Jethro’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Jethro is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Methemoglobinemia?

Oxygen is carried in the blood by hemoglobin. Methemoglobin forms when hemoglobin iron is oxidized, and it cannot carry oxygen in the blood. Methemoglobinemia is a disease where too much methemoglobin is present and the body no longer has the oxygen supply it needs to function. This disease was first described in a mixed breed dog.

ALT Activity

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Jethro inherited one copy of the variant we tested

Why is this important to your vet?

Jethro has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Jethro has this genotype, as ALT is often used as an indicator of liver health and Jethro is likely to have a lower than average resting ALT activity. As such, an increase in Jethro’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Jethro’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A414/643

Map

A1b

Charm City's Black Gold’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A414/643

Charm City's Black Gold’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in the English Springer Spaniels.

A1b is the most common haplogroup found in German Shepherds.

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Through Jethro’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.44

Map

A1b

Charm City's Black Gold’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.44

Charm City's Black Gold’s Haplotype

Part of the A1b haplogroup, this haplotype occurs primarily in Poodles and Belgian Sheepdogs.

Great Danes and Pomeranians have this in common!

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