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“Kenzo”
CCC Epic

Koolie

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Genetic Breed Result

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Koolie

These are intelligent, cheerful, and loyal dogs who can make a great addition to a family. The Koolie is not an aggressive breed and is usually comfortable with new people or new surroundings. Koolies are eager to be trained but this doesn't necessarily mean they're easy to train. When starting obedience training, find an instructor who understands how herding dogs work and you will wind up with an excellent companion dog.

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Health Summary

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Kenzo inherited one variant that you should learn more about.

Degenerative Myelopathy, DM

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Kenzo inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Kenzo’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Kenzo is unlikely to develop this condition due to this variant because he only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Koolies

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Koolies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Koolies

Collie Eye Anomaly (NHEJ1)

Identified in Koolies

Primary Lens Luxation (ADAMTS17)

Identified in Koolies

Cystinuria Type II-A (SLC3A1, Australian Cattle Dog Variant)

Identified in Koolies

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Koolies

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Koolies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

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Through Kenzo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A232

Map

A1a

CCC Epic’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A232

CCC Epic’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs in the South Pacific, as well as Bosnia and Herzegovina. Among breed dogs, this haplotype is most frequent in Labrador Retrievers, Yorkshire Terriers, and Maltese.

Shar Pei dogs think A1a is the coolest!

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Through Kenzo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.10

Map

A1a

CCC Epic’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.10

CCC Epic’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in village dogs throughout Africa and down into the South Pacific. Among breeds, this haplotype occurs in 5 breeds and is most common among Shetland Sheepdogs, Border Collies, and Cairn Terriers.

Dogs with A1a lineage travelled during European Colonial times.

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