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“CASTLE”
GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1

Doberman Pinscher

  • Photo of CASTLE, a Doberman Pinscher  in North Richland Hills, Texas, USA Photo of CASTLE, a Doberman Pinscher  in North Richland Hills, Texas, USA

“Castle is a Grand Champion as well as the #1 Doberman in NADD/AKC Dock Diving in North America ( 2016, 2017 & 2018). At only 3 yrs he is excelling in everything he tries. Titled in Agility and Rally with Dock Diving. He achieved the high recognition of ROM from the DPCA. He has wonderful temperament, drive (on & off switch), focus and athleticism. My dogs are examples of being all-around Dobermans!”

Place of Birth
North Richland Hills, Texas, USA
Current Location
North Richland Hills, Texas, USA
From
North Richland Hills, TX, USA

This dog has been viewed 1141 times and been given 14 wags

Registration

AKC: WS50634106

Genetic Breed Result

Learn how it’s done

Doberman Pinscher

100.0% Doberman Pinscher
Doberman Pinscher Doberman Pinscher
Doberman Pinschers are a strong and athletic breed that are built to guard and protect.
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Genetic Stats


Predicted Adult Weight
Genetic Age
48 human years Learn More
Based on the date of birth provided
Changes to this dog’s profile
Learn More
  • On 6/2/2019 changed name from "GCH CH Radiant Lord Castle DEA DMX2 AMA ROM WAC TKA CA CGCA BCAT" to "GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1"
  • On 1/1/2019 changed name from "GCH CH Radiant Lord Castle DE DMX AM ASX WAC TKI CA CGC BCAT" to "GCH CH Radiant Lord Castle DEA DMX2 AMA ROM WAC TKA CA CGCA BCAT"
  • On 11/27/2017 changed name from "CASTLE" to "GCH Radiant Lord Castle DE DMX AM ASX WAC TKI CA CGC BCAT"
  • On 11/27/2017 changed name from "GCH Radiant Lord Castle DE DMX AM ASX WAC TKI CA CGC BCAT" to "GCH CH Radiant Lord Castle DE DMX AM ASX WAC TKI CA CGC BCAT"

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Our algorithms predict this is the most likely family tree to explain CASTLE’s breed mix, but this family tree may not be the only possible one.

Health Summary

CASTLE is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Dilated Cardiomyopathy, DCM2

CASTLE inherited one copy of the variant we tested

How to interpret this result

CASTLE has one copy of a variant in the TTN gene associated with increased risk for DCM in the American Doberman Pinscher. This variant, also referred to as DCM2, is inherited in a dominant manner, meaning having one or two copies of this variant is thought to confer the same amount of risk. However, the variant is thought to have incomplete penetrance: That is, not all dogs with this variant will ultimately show signs of DCM. Moreover, the impact of this variant in other breeds of dog besides the Doberman has yet to be fully understood. However, if your veterinarian thinks CASTLE shows signs of having DCM based on their diagnostic testing, you now have the opportunity to discuss early treatment. Please consult with your veterinarian regarding a diagnostic and treatment plan for CASTLE. We measure this result using a linkage test.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Von Willebrand Disease Type I

CASTLE inherited one copy of the variant we tested

What does this result mean?

This result should not impact CASTLE’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Von Willebrand Disease Type I?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. vWD is characterized into three types based on clinical severity, serum levels of vWF, and vWF multimer composition. Dogs with Type I vWD have low vWF levels, normal multimer composition, and variable clinical signs.


ALT Activity

CASTLE inherited one copy of the variant we tested

Why is this important to your vet?

CASTLE has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that CASTLE has this genotype, as ALT is often used as an indicator of liver health and CASTLE is likely to have a lower than average resting ALT activity. As such, an increase in CASTLE’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Dilated Cardiomyopathy, DCM1 (PDK4)

Identified in Doberman Pinschers

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a patterned haircoat (kyky)
A Locus (ASIP)
Black/Brown and tan coat color pattern (atat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (Bb)
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Coat Texture (KRT71)
Likely straight coat (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Larger (NN)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Larger (TT)
Body Size (GHR - E191K)
Larger (GG)
Body Size (GHR - P177L)
Larger (CC)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through CASTLE’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B45

Map

B1

GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B45

GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most commonly in Yorkshire Terriers, Doberman Pinschers, Cocker Spaniels, and village dogs in Costa Rica.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Through CASTLE’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.3

Map

A1b

GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.3

GCH CH Radiant Lord Castle NA NAJ OF DEA DMX3 AMA ROM ASA WAC TKA CA CGCA BCAT RL1’s Haplotype

Part of the A1b haplogroup, this haplotype is found in village dogs in Peru and the French Polynesian Islands. It is also common among Doberman Pinscher, Saint Bernard, and Rhodesian Ridgeback.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!