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“Bingley”
CALEDONIA'S MR. BINGLEY

English Toy Spaniel

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“Bingley became a registered therapy dog just after turning one year old, he's been activeling working as a volunteer every since. He also enjoys playing on the agility field.”

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Registration

AKC: TS28850002

Genetic Breed Result

English Toy Spaniel

“Bingley”
CALEDONIA'S MR. BINGLEY

embk.me/i/caledoniasmrbingley

English Toy Spaniel

The English Toy Spaniel is a small, kind, and lovable little dog. These guys were held in high regard by English royalty. They are wonderfully suited for appartment living and make great lapdogs.

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Genetic Stats

Predicted Adult Weight

19 lbs

Genetic Age
44 human years

Based on the date of birth provided

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Health Summary

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Bingley is at increased risk for one genetic health condition.

Intervertebral Disc Disease (Type I)

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Bingley inherited both copies of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Bingley’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Bingley have not yet been the focus of research studies, our data indicates that Bingley is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Bingley’s breed, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Breed-Relevant Genetic Conditions

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Dry Eye Curly Coat Syndrome (FAM83H Exon 5)

Identified in English Toy Spaniels

Muscular Dystrophy (DMD, Cavalier King Charles Spaniel Variant 1)

Identified in English Toy Spaniels

Episodic Falling Syndrome (BCAN)

Identified in English Toy Spaniels

Additional Genetic Conditions

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Clinical Tools

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (EE)
K Locus (CBD103)
More likely to have a patterned haircoat (kyky)
Intensity Loci LINKAGE
Any light hair likely apricot or red (Intense Red Pigmentation)
A Locus (ASIP)
Black/Brown and tan coat color pattern (atat)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (DD)
B Locus (TYRP1)
Black or gray hair and skin (BB)
S Locus (MITF)
Likely to have little to no white in coat (SS)
H Locus (Harlequin)
hh
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely long coat (TT)
Shedding (MC5R)
Likely light to moderate shedding (TT)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Unlikely to have hind dew claws (CC)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Larger (GG)
Body Size (STC2)
Smaller (AA)
Body Size (GHR - E191K)
Smaller (AA)
Body Size (GHR - P177L)
Smaller (TT)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)
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Through Bingley’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A26a

Map

A1d

CALEDONIA'S MR. BINGLEY’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A26a

CALEDONIA'S MR. BINGLEY’s Haplotype

Part of the large A1d haplogroup, we have not yet detected this haplotype in any of our village dogs. Among the 6 breeds we see it in, it appears most frequently in Newfoundlands, Cavalier King Charles Spaniels, and soft coated Wheaten Terriers.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Bingley’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

H3

Map

A2b

CALEDONIA'S MR. BINGLEY’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

H3

CALEDONIA'S MR. BINGLEY’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Cavalier King Charles Spaniels, Brittanys, Soft Coated Wheaten Terriers, and village dogs in Lebanon.

Some other Embark dogs with this haplotype:

A2b is found in the Daschund breed.

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