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Cadvan

Mixed Ancestry

“Small dogs can do everything big dogs can!”

Instagram tag
@dog.first.small.second

Place of Birth

United Kingdom

Current Location

Darlington, England, United Kingdom

From

Morecambe, England, United Kingdom

This dog has been viewed and been given 3 wags

Genetic Breed Result

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Chihuahua

Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.

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Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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Yorkshire Terrier

Petite but proud, the Yorkshire terrier is a popular toy breed with a silky, low-shedding coat.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Pug

The Pug is a breed of dog with a wrinkly, short-muzzled face and curled tail. Pugs are known for being sociable and gentle companion dogs.

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Dogs Like Cadvan

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Discover dogs who share a similar breed mix to Cadvan. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Chihuahua
Russell-type Terrier
Yorkshire Terrier
Pomeranian
Pug

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Here’s what Cadvan’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Cadvan’s breed mix.
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Health Summary

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Cadvan is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Cadvan inherited one copy of the variant we tested

How to interpret this result

Cadvan has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

ALT Activity

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Cadvan inherited both copies of the variant we tested

Why is this important to your vet?

Cadvan has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Cadvan's ALT activity above their current, healthy, ALT activity. As an increase above Cadvan’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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May-Hegglin Anomaly

Identified in Pugs

Pyruvate Kinase Deficiency

Identified in Pugs

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Progressive Retinal Atrophy, rcd3

Identified in Pomeranians

Progressive Retinal Atrophy, prcd

Identified in Chihuahuas and Yorkshire Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Chihuahuas

Primary Lens Luxation

Identified in Russell-type Terriers and Yorkshire Terriers

Urate Kidney & Bladder Stones

Identified in Pomeranians and Russell-type Terriers

Neuronal Ceroid Lipofuscinosis 7, NCL 7

Identified in Chihuahuas

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Chihuahuas and Russell-type Terriers

Degenerative Myelopathy, DM

Identified in Pugs and Russell-type Terriers

Oculocutaneous Albinism, OCA

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets

Identified in Pomeranians

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Cadvan’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Cadvan’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Cadvan’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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Through Cadvan’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.39/57

Map

A1a

Cadvan’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.39/57

Cadvan’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Dogs with A1a lineage travelled during European Colonial times.

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