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Buttercup

Chinese Shar-Pei

  • Buttercup, a Chinese Shar-Pei tested with EmbarkVet.com Buttercup, a Chinese Shar-Pei tested with EmbarkVet.com

No bio has been provided yet

Current Location

Bloomington, Illinois, USA

From

Richardson, TX, USA

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Genetic Breed Result

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Chinese Shar-Pei

Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.

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Here’s what Buttercup’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Buttercup’s breed mix.

Breed Reveal Video

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Health Summary

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Buttercup inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Primary Open Angle Glaucoma and Primary Lens Luxation

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Buttercup inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Buttercup’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Buttercup is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Primary Open Angle Glaucoma and Primary Lens Luxation?

Glaucoma is the result of high intraocular pressure, and if left untreated, can lead to pain and vision loss. The "angle" of primary open glaucoma (POAG) refers to the intersection of the cornea and the iris: this is where aqueous humor (clear fluid filling the eye) must flow to exit the eye. In open angle glaucoma, the iridocorneal angle remains unchanged, and other factors contribute to increased resistance to outflow.

ALT Activity

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Buttercup inherited one copy of the variant we tested

Why is this important to your vet?

Buttercup has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Buttercup has this genotype, as ALT is often used as an indicator of liver health and Buttercup is likely to have a lower than average resting ALT activity. As such, an increase in Buttercup’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever

Identified in Chinese Shar-Peis

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Buttercup’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B77

Map

B1

Buttercup’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B77

Buttercup’s Haplotype

Part of the B1 haplogroup, this haplotype occurs most frequently in Japanese Chins.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Buttercup inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Buttercup is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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