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Little Bear

Mixed Ancestry

“Little Bear is a rescue from Alabama. We do not know how old he is.”

Instagram tag
@Buddylittlebear

Current Location

Massachusetts, USA

From

Alabama, USA

This dog has been viewed and been given 5 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from this distant ancestor:

Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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Shih Tzu

This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.

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Russell-type Terrier

These small, energetic terriers, developed in 19th century England for hunting small game, are now some of the best agility dogs around.

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Dogs Like Little Bear

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Discover dogs who share a similar breed mix to Little Bear. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Australian Cattle Dog
Shih Tzu
Russell-type Terrier
Supermutt

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Changes to this dog’s profile
  • On 12/27/2017 changed handle from "littlebear4" to "littlebear13"
  • On 12/27/2017 changed handle from "littlebear13" to "buddylittlebear"
Here’s what Little Bear’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Little Bear’s breed mix.
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Health Summary

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Little Bear is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Primary Lens Luxation

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Little Bear inherited one copy of the variant we tested

How to interpret this result

Little Bear has one copy of a variant in the ADAMTS17 gene and is at some risk for developing PLL. This variant is known to have an additive effect, so while dogs with one copy of the variant like Little Bear have a higher risk than dogs with two healthy alleles at ADAMTS17, their risk is much lower than a dog with two copies of the variant. Actual risk associated with having one copy of this variant appears to vary in a breed-specific manner. A study published by Gould et al 2011 supports that Tibetan Terriers with one copy of the variant have minimal risk of developing PLL, whereas this risk can range from 2-20% in other terrier breeds. Please consult with your veterinarian to discuss the best ways to monitor Little Bear's eyes and vision.

What is Primary Lens Luxation?

PLL occurs when the lens spontaneously detaches from its normal residence within the pupil, leading to reduced visual acuity. Anterior lens luxation is when the lens falls forward and posterior lens luxation is when the lens falls backwards in the eye.

Progressive Retinal Atrophy, prcd

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Little Bear inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Little Bear’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Little Bear is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

ALT Activity

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Little Bear inherited one copy of the variant we tested

Why is this important to your vet?

Little Bear has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Little Bear has this genotype, as ALT is often used as an indicator of liver health and Little Bear is likely to have a lower than average resting ALT activity. As such, an increase in Little Bear’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Australian Cattle Dogs

Prekallikrein Deficiency

Identified in Shih Tzus

Severe Combined Immunodeficiency, SCID

Identified in Russell-type Terriers

Collie Eye Anomaly

Identified in Australian Cattle Dogs

Cystinuria Type II-A

Identified in Australian Cattle Dogs

Urate Kidney & Bladder Stones

Identified in Russell-type Terriers

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Cattle Dogs

Late Onset Spinocerebellar Ataxia

Identified in Russell-type Terriers

Spinocerebellar Ataxia with Myokymia and/or Seizures

Identified in Russell-type Terriers

Degenerative Myelopathy, DM

Identified in Russell-type Terriers

Myotonia Congenita

Identified in Australian Cattle Dogs

Intervertebral Disc Disease (Type I)

Identified in Russell-type Terriers and Shih Tzus

Additional Genetic Conditions

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Through Little Bear’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B47

Map

B1

Little Bear’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B47

Little Bear’s Haplotype

Part of the large B1 haplogroup, we have spotted this haplotype in village dogs in South America, Africa, the Middle East, and South Asia. Among the 8 breeds we have sampled it in, this haplotype occurs most frequently in Newfoundlands, Australian Cattle Dogs, and Pembroke Welsh Corgis.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Little Bear’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.4

Map

A1a

Little Bear’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.4

Little Bear’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs in Colombia. It is common in small dogs like Dachshund, Miniature Dachshund, and Chihuahuas, but can also be found in larger breeds like Golden Retrievers.

Dogs with A1a lineage travelled during European Colonial times.

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