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“Teijo”
CH Buckwheater's Tinker Tailor Soldier Skye

Skye Terrier

No bio has been provided yet

Place of Birth

Ojakkala, Finland

Current Location

San Diego, CA, USA

From

Ojakkala, Finland

This dog has been viewed and been given 2 wags

Registration

American Kennel Club (AKC): RN34245901

Genetic Breed Result

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Skye Terrier

Originally kept as hunting dogs, Skye Terriers are now more commonly kept as companions, and prized for their loyalty and loving personalities.

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Changes to this dog’s profile
  • On 9/21/2023 changed name from "Buckwheater's Tinker Tailor Soldier Skye" to "CH Buckwheater's Tinker Tailor Soldier Skye"

Health Summary

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Teijo is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Teijo inherited both copies of the variant we tested

What does this result mean?

Follow-up by our experts indicates that this genetic variant is associated with an increase to Teijo’s risk for developing Intervertebral Disc Disease (Type I).

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. While dogs with similar breeds to Teijo have not yet been the focus of research studies, our data indicates that Teijo is likely to be at increased risk.

Impact on Breeding

While further investigation is warranted to determine the clinical presentation and penetrance in Teijo’s breed, we recommend taking this genetic result into account when making breeding decisions.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Craniomandibular Osteopathy, CMO

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Teijo inherited one copy of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Teijo will develop Craniomandibular Osteopathy, CMO.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with Teijo's breed have been studied to know whether or not this variant will increase Teijo's risk of developing this disease.

Impact on Breeding

Research into the clinical impact of this variant is ongoing. We recommend tracking this genetic result and incidence of Craniomandibular Osteopathy, CMO in your breeding program and related dogs.

What is Craniomandibular Osteopathy, CMO?

A noncancerous, proliferative bone disease that commonly affects the lower jaw and tympanic bullae, CMO is best known in the West Highland White Terrier, Scottish Terrier, and Cairn Terrier; though it has been observed sporadically in larger dog breeds.

ALT Activity

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Teijo inherited both copies of the variant we tested

Why is this important to your vet?

Teijo has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Teijo's ALT activity above their current, healthy, ALT activity. As an increase above Teijo’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

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Through Teijo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A233

Map

A1e

CH Buckwheater's Tinker Tailor Soldier Skye’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A233

CH Buckwheater's Tinker Tailor Soldier Skye’s Haplotype

Part of the large A1e haplogroup, we see this haplotype in village dogs across Central Africa through the Middle East and into South Asia. As for breeds, we see it in the highest frequency among Irish Wolfhounds, with some detections in Greyhounds, Posavac Hounds, and Beagles as well.

Irish Wolfhounds are a consistent carrier of A1e.

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Through Teijo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.46

Map

A1a

CH Buckwheater's Tinker Tailor Soldier Skye’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.46

CH Buckwheater's Tinker Tailor Soldier Skye’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Dogs with A1a lineage travelled during European Colonial times.

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