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Bubba

Australian Shepherd Group

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“Bubba was seized after the passing of an Australian shepherd show dog breeder/hoarder in rural Indiana. He lived in a tiny crate with feces and dead rodents. He had flea dermatitis, dermal yeast infections, a UTI, and HW. He is now neutered and available for adoption with Newman Nation. He was estimated 10-13 yrs old in November 2019 but acts like a puppy. As soon as he got to the house, you could tell he'd waited his whole life to be a house dog. He LOVES to play.”

Place of Birth

Morocco, IN, USA

Current Location

Urbana, Illinois, USA

From

Morocco, IN, USA

This dog has been viewed and been given 24 wags

Genetic Breed Result

Bubba

Bubba

Australian Shepherd Group
100.0% Australian Shepherd

Australian Shepherd

Australian Shepherds are an energetic mid-sized breed that make the perfect companion.

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Genetic Stats

Wolfiness

0.3 % LOW

Predicted Adult Weight

65 lbs

Genetic Age
109 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Australian Shepherd

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Health Summary

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Bubba is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Multiple Drug Sensitivity

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Bubba inherited one copy of the variant we tested

How to interpret this result

Bubba has one copy of a variant at the ABCB1 gene and is at risk for displaying adverse drug reactions. While he may not be as severely affected as a dog with two copies of the ABCB1 drug sensitivity allele, normal dosages of drugs could still have potentially severe effects on Bubba. Please inform your veterinarian that Bubba carries this variant; it is essential that they know this information before prescribing drugs.

What is Multiple Drug Sensitivity?

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with a mutation in the ABCB1 gene.

Dilated Cardiomyopathy, DCM1

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Bubba inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Bubba will develop this disease.

Scientific Basis

Dogs with similar breeds to Bubba are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Bubba.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Bubba inherited one copy of the variant we tested

Why is this important to your vet?

Bubba has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Bubba has this genotype, as ALT is often used as an indicator of liver health and Bubba is likely to have a lower than average resting ALT activity. As such, an increase in Bubba’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, prcd

Identified in Australian Shepherds and Australian Shepherds

Collie Eye Anomaly

Identified in Australian Shepherds and Australian Shepherds

Canine Multifocal Retinopathy, cmr1

Identified in Australian Shepherds and Australian Shepherds

Hereditary Cataracts

Identified in Australian Shepherds and Australian Shepherds

Urate Kidney & Bladder Stones

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 6, NCL 6

Identified in Australian Shepherds and Australian Shepherds

Neuronal Ceroid Lipofuscinosis 8, NCL 8

Identified in Australian Shepherds and Australian Shepherds

Craniomandibular Osteopathy, CMO

Identified in Australian Shepherds and Australian Shepherds

Additional Genetic Conditions

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Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Red Pigment Intensity LINKAGE
I (Intensity) Loci
Any light fur likely yellow or tan
Brown or Black Pigment
B (Brown) Locus
Brown fur and skin
Color Dilution
D (Dilute) Locus
No Result
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have patterned fur
Body Pattern
A (Agouti) Locus
Black/Brown and tan coat color pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
Not saddle tan patterned
White Spotting
S (White Spotting) Locus
Likely to have little to no white in coat
Merle
M (Merle) Locus
Likely to appear merle or "phantom merle"
Harlequin
No impact on coat pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely long coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Intermediate
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Bubba’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A604

Map

A1d

Bubba’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A604

Bubba’s Haplotype

Part of the A1d haplogroup, the A604 haplotype occurs most commonly in Australian Shepherds. It's a rare find!

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Bubba’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.46

Map

A1a

Bubba’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.46

Bubba’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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