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Bruce

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“Bruce is a rescue from a local rescue group. He's a jerk.”

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@rebekah_lw

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Genetic Stats

Wolfiness

4.9 % HIGH

Predicted Adult Weight

65 lbs

Genetic Age
90 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Alaskan Malamute
Gray Wolf
German Shepherd Dog
Siberian Husky

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Health Summary

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Bruce has one variant that you should let your vet know about.

ALT Activity

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Bruce inherited both copies of the variant we tested

Why is this important to your vet?

Bruce has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Bruce's ALT activity above their current, healthy, ALT activity. As an increase above Bruce’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Alaskan Malamutes

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLADIII

Identified in German Shepherd Dogs

Day Blindness

Identified in German Shepherd Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Degenerative Myelopathy, DM

Identified in German Shepherd Dogs

Polyneuropathy, AMPN

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Red Pigment Intensity LINKAGE
I (Intensity) Loci
No impact on coat pattern
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
No dark mask or grizzle facial fur patterns
White Spotting
S (White Spotting) Locus
Likely to have some white areas in coat
Harlequin
hh
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Larger
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Larger
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance
Appetite LINKAGE
Normal food motivation
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Through Bruce’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Bruce’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Bruce’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Through Bruce’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8

Map

A1a

Bruce’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8

Bruce’s Haplotype

Part of the large A1a haplogroup, this very common haplotype occurs in village dogs throughout the world (including southeast Asia, which is uncommon for A1a’s). Among the 25 breeds we see this haplotype in, it occurs most frequently in Labrador Retriever, Vizsla, and English Springer Spaniel.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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