Chicha inherited one copy of the variant we tested
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Place of Birth
Serbia
Current Location
Hagerstown, MD, USA
From
Serbia
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Changes to this dog’s profile
- On 10/1/2021 changed handle from "brendadivna" to "brendaxxxvi"
- On 10/1/2021 changed name from "Brenda Divna" to "Brenda XXXVI"
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Health Summary
Chicha inherited one variant that you should learn more about.
Degenerative Myelopathy, DM
What does this result mean?
This variant should not impact Chicha’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Chicha is unlikely to develop this condition due to this variant because she only has one copy of the variant.
Impact on Breeding
Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.
What is Degenerative Myelopathy, DM?
The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.
Breed-Relevant Genetic Conditions
Multiple Drug Sensitivity (ABCB1)
Identified in German Shepherd Dogs
Variant not detected
Hemophilia A (F8 Exon 11, German Shepherd Variant 1)
Identified in German Shepherd Dogs
Variant not detected
Hemophilia A (F8 Exon 1, German Shepherd Variant 2)
Identified in German Shepherd Dogs
Variant not detected
Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected
Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F)
Identified in German Shepherd Dogs
Variant not detected
Day Blindness (CNGA3 Exon 7, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected
Urate Kidney & Bladder Stones (SLC2A9)
Identified in German Shepherd Dogs
Variant not detected
Anhidrotic Ectodermal Dysplasia (EDA Intron 8)
Identified in German Shepherd Dogs
Variant not detected
Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)
Identified in German Shepherd Dogs
Variant not detected
Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected