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“Brazen”
NovaMals Autumn Uprising

Alaskan Malamute

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@novamal_alaskanmalamutes

Place of Birth

Lawrencetown, Nova Scotia, Canada

Current Location

Lawrencetown, Nova Scotia, Canada

From

Lawrencetown, Nova Scotia, Canada

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Registration

Canadian Kennel Club (CKC): Gu3969319

Genetic Breed Result

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Alaskan Malamute

The Alaskan Malamute is a large, fluffy spitz breed recognized as being one of the most ancient breeds of dogs. The forebears to the modern Malamute crossed the Bering Strait with their owners over 4,000 years ago. Their size, thick coat, and work drive make them ideal dogs for pulling sleds, but they also make amicable companions.

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Genetic Stats

Predicted Adult Weight

101 lbs

Genetic Age
31 human years

Based on the date of birth provided

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Changes to this dog’s profile
  • On 8/7/2022 changed name from "Brazen" to "NovaMals Autumn Uprising"

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Health Summary

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Brazen has one variant that you should let your vet know about.

ALT Activity

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Brazen inherited both copies of the variant we tested

Why is this important to your vet?

Brazen has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Brazen's ALT activity above their current, healthy, ALT activity. As an increase above Brazen’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Brazen’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A91/11

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A1d

NovaMals Autumn Uprising’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A91/11

NovaMals Autumn Uprising’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 29 breeds that we have detected it in to date, the most frequent breeds we see expressing it are Afghan Hounds, Greater Swiss Mountain Dogs, and Borzois.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Brazen’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C

Haplotype

H5a

Map

C

NovaMals Autumn Uprising’s Haplogroup

C is a relatively rare paternal lineage. The dog populations which bear C are a disparate bunch. The Akita and Shiba Inu are Japanese breeds, the former of which seems to have roots in the Jomon population of hunter-gatherers which were present in the islands of Japan before the ancestors of the modern Japanese arrived. The New Guinea Singing Dog, Samoyed, and Alaska Malamute are all disparate breeds that also represent the C lineage. One village dog from Peru also bore this lineage. This wide distribution and diversity suggest C is not a recently expanded lineage. It likely represents a canid lineage which diversified sometime around the Last Glacial Maximum, when the dogs of Siberia and Oceania split off and went their separate ways.

H5a

NovaMals Autumn Uprising’s Haplotype

Part of the C haplogroup, this haplotype occurs most commonly in Akitas and Alaskan Malamutes.

Some other Embark dogs with this haplotype:

The Shiba Inu descends from this relativey rare haplogroup.

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