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Brandywine Verity

English Shepherd

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“Fourth-generation operational SAR dog. Useful farm dog; kind to her stock, good on light poultry to stubborn hogs, watchful night guardian. Outgoing, kid-loving, puppy-crazy, dog neutral, mature and thoughtful. A bit over-scrupulous about right conduct, especially her own. Lisa Simpson vibe. She's tall and gracile, pointy-headed and fluffy-butted. OFA Excellent.”

Place of Birth

Harmony, PA, USA

Current Location

Harmony, Pennsylvania, USA

From

Harmony, PA, USA

This dog has been viewed and been given 2 wags

Registration

English Shepherd Club (ESC): ESC-4919

Genetic Breed Result

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English Shepherd

A farmer's helper, a loyal companion, a child's shadow: The English Shepherd.

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Health Summary

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Brandywine Verity has one variant that you should let your vet know about.

ALT Activity

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Brandywine Verity inherited both copies of the variant we tested

Why is this important to your vet?

Brandywine Verity has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Brandywine Verity's ALT activity above their current, healthy, ALT activity. As an increase above Brandywine Verity’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in English Shepherds

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in English Shepherds

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in English Shepherds

Collie Eye Anomaly (NHEJ1)

Identified in English Shepherds

Urate Kidney & Bladder Stones (SLC2A9)

Identified in English Shepherds

Additional Genetic Conditions

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Brandywine Verity’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1c

Map

B1

Brandywine Verity’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1c

Brandywine Verity’s Haplotype

Part of the large B1 haplogroup, we have detected this haplotype in Mexico and Lebanon village dogs. Among the 12 breeds that we have spotted this haplotype in, it occurs most frequently in Border Collies, Australian Shepherd Dogs, and West Highland white Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Brandywine Verity inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Brandywine Verity is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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