Venn diagram

Compare your dogs to Brady Select one to begin:

Brady

Labrador Retriever

“He is named for Tom Brady”

Current Location

North Carolina, USA

This dog has been viewed and been given 0 wags

Genetic Breed Result

Loading...

Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

Learn More

Loading...

Start a conversation! Message this dog’s humans.

Loading...

Explore

Health Summary

warn icon

Brady inherited two variants that you should learn more about.

Progressive Retinal Atrophy, prcd

warn icon

Brady inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Brady’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Brady is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

Exercise-Induced Collapse, EIC

warn icon

Brady inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Brady’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Brady is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Exercise-Induced Collapse, EIC?

EIC has been linked to a mutation in the DNM1 gene, which codes for the protein dynamin. In the neuron, dynamin trucks neurotransmitter-filled vesicles from the cell body, where they are generated, to the dendrites. It is hypothesized in dogs affected with EIC, the mutation in DNM1 disrupts efficient neurotransmitter release, leading to a cessation in signalling and EIC.

Breed-Relevant Genetic Conditions

good icon

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Day Blindness

Identified in Labrador Retrievers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in Labrador Retrievers

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Labrador Retrievers

Narcolepsy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore

Through Brady’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A230

Map

A1a

Brady’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A230

Brady’s Haplotype

Part of the large A1a haplogroup, we have spotted this haplotype among village dogs in Peru. This haplotype does not occur in many breeds, but it occurs with high frequency in Labrador Retrievers and less frequently in Flat-Coated Retrievers and German Shepherd Dogs.

Shar Pei dogs think A1a is the coolest!

Loading...

Explore

Through Brady’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.10

Map

A2b

Brady’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.10

Brady’s Haplotype

Part of the A2b haplogroup, this haplotype occurs most commonly in Labrador Retrievers, Rottweilers, Curly-Coated Retrievers, Dandie Dinmont Terriers, and village dogs throughout the world.

A2b is found in the Daschund breed.

Loading...

Explore