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Bonnie

Mixed Breed

“Bonnie was adopted from a shelter when she was almost 4 months old. She loves playing chase with other puppies and cuddling on the couch.”

This dog has been viewed 578 times and been given 2 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

41.6% American Pit Bull Terrier
20.3% Labrador Retriever
8.6% Australian Cattle Dog
8.2% American Staffordshire Terrier
8.0% Chow Chow
4.1% Collie
9.2% Supermutt

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

American Pit Bull Terrier American Pit Bull Terrier
Few dogs are more recognizable than the American Pit Bull Terrier. While they originated in the British Isles and are descendants of the Mastiff-type dogs introduced to England in antiquity, the American Pit Bull Terrier was brought over to the United States by English immigrants in the 1800s. They quickly became one of the most popular and widespread breeds there.
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Labrador Retriever Labrador Retriever
The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.
Learn More
Australian Cattle Dog Australian Cattle Dog
A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.
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American Staffordshire Terrier American Staffordshire Terrier
American Staffordshire Terrier's are powerul but playful dogs, that are both loyal and affectionate with their owners.
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Chow Chow Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. He can be aloof — if you’re looking for a cuddle buddy, this probably isn’t the best breed for you — and downright suspicious of strangers. But for the right person, he’s a fiercely loyal companion.
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Collie Collie
Collies are attractive herding dogs, boasting a beautiful coat while being highly intelligent. They also make for extremely loyal and sweet family pets.
Learn More
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Genetic Stats

Wolfiness: 0.3 % LOW Learn More
Predicted Adult Weight: 46 lbs Learn More
Genetic Age: 16 human years Learn More

Explore other Embark dogs who have breed mixes that are similar to Bonnie’s.
A Mix Match of 100 means they are the exact same breed mix!

Breed Mix Matches

DNA Breed Origins

What’s this?
Breed colors:
American Pit Bull Terrier
Labrador Retriever
Australian Cattle Dog
American Staffordshire Terrier
Chow Chow
Collie
Supermutt

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Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Changes to this dog’s profile
  • On 5/17/2018 changed handle from "bonnie29" to "bonniethepup"
What’s this?

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed American Pit Bull Terrier / American Staffordshire Terrier mix Labrador Retriever / Chow Chow mix American Pit Bull Terrier / Collie mix Labrador Retriever / Australian Cattle Dog mix American Pit Bull Terrier American Staffordshire Terrier mix Labrador Retriever Chow Chow mix American Pit Bull Terrier Collie mix Labrador Retriever mix Australian Cattle Dog mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Bonnie’s breed mix, but this family tree may not be the only possible one.

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Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
0
CARRIER
165
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Bonnie has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Bonnie has t…

Not At Risk

Good news! Bonnie did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Bonnie does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Bonnie’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Bonnie is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Bonnie tested clear for 30 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in Collies, but not Bonnie.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Labrador Retrievers, but not Bonnie.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A largely benign disease of red blood cell shape, elliptocytosis rarely causes symptoms. Upon examinatino of a blood smear, however, affected dogs have elongated, oval or…

Seen in Labrador Retrievers, Chow Chows, but not Bonnie.

Cyclic Neutropenia, Gray Collie Syndrome
(AP3B1 Exon 20)
Blood

This is a disease of neutrophil production where the number of circulating neutrophils drops precipitously, leaving dogs prone to bacterial infections, and then slowly re…

Seen in Collies, but not Bonnie.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Labrador Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Labrador Retrievers, but not Bonnie.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, Australian Cattle Dogs, but not Bonnie.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Bonnie.

Progressive Retinal Atrophy - crd1
(PDE6B)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Bonnie.

Progressive Retinal Atrophy - crd2
(IQCB1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Bonnie.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Labrador Retrievers, but not Bonnie.

Collie Eye Anomaly, Choroidal Hypoplasia
(NHEJ1)
Eyes

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia and is a developmental disease of the choroid. The ch…

Seen in Collies, but not Bonnie.

Achromatopsia
(CNGA3 Exon 7 Labrador Retriever Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in Labrador Retrievers, but not Bonnie.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Australian Cattle Dogs, but not Bonnie.

Macular Corneal Dystrophy (MCD)
(CHST6)
Eyes

A disease of middle-aged dogs, MCD was first characterized in the Labrador Retriever. Affected dogs begin to show clouding of the eyes and visual impairment due to abnorm…

Seen in Labrador Retrievers, but not Bonnie.

Cystinuria Type II-A
(SLC3A1)
Kidney and Bladder

A disease of cystine accumulation, affected dogs are prone to developing cystine kidney and bladder stones, which if caught early can be managed with dietary changes, inc…

Seen in Australian Cattle Dogs, but not Bonnie.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Bonnie.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia - NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Bonnie.

Neuronal Ceroid Lipofuscinosis 1
(CLN5 Exon 4 Variant 1)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Bonnie.

Neuronal Ceroid Lipofuscinosis
(CLN8)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Australian Cattle Dogs, but not Bonnie.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in American Pit Bull Terriers, Labrador Retrievers, Australian Cattle Dogs, American Staffordshire Terriers, Chow Chows, Collies, but not Bonnie.

Narcolepsy
(HCRTR2 Intron 6)
Brain and Spinal Cord

A neurologic condition characterized by daytime sleepiness and fragmented sleep cycles, affected dogs also exhibit episodes of cataplexy, a sudden complete loss of muscle…

Seen in Labrador Retrievers, but not Bonnie.

Centronuclear Myopathy
(PTPLA)
Muscular

This muscle disorder is characterized by exercise intolerance, weight loss, and muscle wasting. While abnormal tendon reflexes can be observed as early as one month, the …

Seen in Labrador Retrievers, but not Bonnie.

Exercise-Induced Collapse
(DNM1)
Muscular

First characterized in field-trial lines of Labrador Retriever dogs, this muscle disorder can cause episodes of muscle weakness and sometimes collapse; after recovering, …

Seen in Labrador Retrievers, but not Bonnie.

Myotonia Congenita
(CLCN1 Exon 23)
Muscular

This condition is characterized by prolonged muscle contraction and stiffness that usually resolves with normal exercise, though physical therapy can be beneficial. The g…

Seen in Australian Cattle Dogs, but not Bonnie.

Myotubular Myopathy 1, X-linked Myotubular Myopathy
(MTM1)
Muscular

This is a degenerative muscle disease first characterized in the Labrador Retriever. Affected dogs present as puppies with failure to thrive and weakness; this rapidly pr…

Seen in Labrador Retrievers, but not Bonnie.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in American Pit Bull Terriers, Labrador Retrievers, Australian Cattle Dogs, American Staffordshire Terriers, Chow Chows, Collies, but not Bonnie.

Congenital Myasthenic Syndrome
(COLQ)
Neuro-muscular

This is a non-progressive disease characterized by episodes of exercise intolerance and weakness; some forms have been shown to respond to medical treatment. Though it ha…

Seen in Labrador Retrievers, but not Bonnie.

Hereditary Nasal Parakeratosis
(SUV39H2)
Skin & Connective Tissues

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog. HNPK isn't usually as upsetting to the dog as it …

Seen in Labrador Retrievers, but not Bonnie.

Oculoskeletal Dysplasia 1, Dwarfism-Retinal Dysplasia
(COL9A3, Labrador Retriever)
Skeletal

A developmental disease described in the Labrador Retriever and the Samoyed, affected dogs can show signs very early in life and can include dramatic short-limbed dwarfis…

Seen in Labrador Retrievers, but not Bonnie.

Skeletal Dysplasia 2
(COL11A2)
Skeletal

A disease of skeletal development, this causes dogs to have abnormally short legs but similar body lengths compared to unaffected dogs, and can be observed by the time do…

Seen in Labrador Retrievers, but not Bonnie.

Other Conditions: Clear of 135

Bonnie is clear of 135 other genetic diseases that Embark tests for.

Explore:

Family tree

Traits

Maternal Haplotype

Paternal Haplotype

Jump to:

Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Eme
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
ayat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Bonnie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C3/14

Map

C2

Bonnie’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C3/14

Bonnie’s Haplotype

Part of the C2 haplogroup, this common haplotype occurs most often in English Setters, Cairn Terriers, Labrador Retrievers, and village dogs in Peru, Fiji, and across Africa.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

Explore:

Family tree

Health

Traits

Paternal Haplotype

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Bonnie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Explore:

Family tree

Health

Traits

Maternal Haplotype