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Cash

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Changes to this dog’s profile
  • On 2/23/2021 changed name from "Rosie male pup" to "Cash"
  • On 12/26/2020 changed name from "Bonnie male pup" to "Rosie male pup"

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Health Summary

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Cash has one variant that you should let your vet know about.

ALT Activity

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Cash inherited one copy of the variant we tested

Why is this important to your vet?

Cash has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Cash has this genotype, as ALT is often used as an indicator of liver health and Cash is likely to have a lower than average resting ALT activity. As such, an increase in Cash’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Bernese Mountain Dogs, Standard Poodles, and more

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Cocker Spaniels, Standard Poodles, and more

Familial Nephropathy (COL4A4 Exon 3, Cocker Spaniel Variant)

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in Cocker Spaniels

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Bernese Mountain Dogs and Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles and Small Poodles

Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant)

Identified in Cocker Spaniels

Exercise-Induced Collapse, EIC (DNM1)

Identified in Cocker Spaniels

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles and Small Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Cocker Spaniels, Standard Poodles, and more

Additional Genetic Conditions

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