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Bonnie

Mixed Ancestry

  • Bonnie, a Labrador Retriever and Cocker Spaniel mix tested with EmbarkVet.com Bonnie, a Labrador Retriever and Cocker Spaniel mix tested with EmbarkVet.com
    The yard Bonnie was rescued from.

“Bonnie was rescued from a hoarding situation of 30+ dogs. She had spent her whole life living in a backyard. She was taken in to rescue on March 28, 2021, and came to my house, as a foster on May 17th, 2020.”

Place of Birth

Dallas, Texas, USA

Current Location

Carrollton, Texas, USA

From

Dallas, Texas, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Chinese Shar-Pei

Few dog breeds are more recognizable than the wrinkly Chinese Shar-Pei. This Chinese breed is often compared to a hippopotamus due to its thick muzzle. They also have a characteristic rough, bristly coat, which is how the breed got its name (“Shar-Pei” means “sand skin”). Despite their goofy appearance, Shar-Peis are serious, independent dogs who will loyally protect their owners.

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Dalmatian

Best known as the star of Disney’s 101 Dalmatians, this sleek and athletic dog breed has a history that goes back several hundred years. He started out as a coach dog but has also served in many other capacities, including hunter, firehouse dog, and circus performer. As charming in life as in film, he goes from gallant to goofy to gallant again in the blink of an eye, and loves to be a part of everything his family does.

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Miniature Pinscher

The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.

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Dogs Like Bonnie

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Discover dogs who share a similar breed mix to Bonnie. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Labrador Retriever
Cocker Spaniel
Chow Chow
Chinese Shar-Pei
Dalmatian
Border Collie
Miniature Pinscher
Supermutt

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Here’s what Bonnie’s family tree may have looked like.
Bonnie
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Chinese Shar-Pei / Miniature Pinscher mix Dalmatian / Border Collie mix Labrador Retriever / Chow Chow mix Cocker Spaniel mix Chinese Shar-Pei Miniature Pinscher mix Dalmatian mix Border Collie mix Labrador Retriever Chow Chow Cocker Spaniel Mixed
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Bonnie’s breed mix.

Breed Reveal Video

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Health Summary

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Bonnie is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Primary Lens Luxation

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Bonnie inherited one copy of the variant we tested

How to interpret this result

Bonnie has one copy of a variant in the ADAMTS17 gene and is at some risk for developing PLL. This variant is known to have an additive effect, so while dogs with one copy of the variant like Bonnie have a higher risk than dogs with two healthy alleles at ADAMTS17, their risk is much lower than a dog with two copies of the variant. Actual risk associated with having one copy of this variant appears to vary in a breed-specific manner. A study published by Gould et al 2011 supports that Tibetan Terriers with one copy of the variant have minimal risk of developing PLL, whereas this risk can range from 2-20% in other terrier breeds. Please consult with your veterinarian to discuss the best ways to monitor Bonnie's eyes and vision.

What is Primary Lens Luxation?

PLL occurs when the lens spontaneously detaches from its normal residence within the pupil, leading to reduced visual acuity. Anterior lens luxation is when the lens falls forward and posterior lens luxation is when the lens falls backwards in the eye.

ALT Activity

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Bonnie inherited one copy of the variant we tested

Why is this important to your vet?

Bonnie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Bonnie has this genotype, as ALT is often used as an indicator of liver health and Bonnie is likely to have a lower than average resting ALT activity. As such, an increase in Bonnie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in Border Collies

Canine Elliptocytosis

Identified in Labrador Retrievers

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Trapped Neutrophil Syndrome, TNS

Identified in Border Collies

Progressive Retinal Atrophy, prcd

Identified in Cocker Spaniels and Labrador Retrievers

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Collie Eye Anomaly

Identified in Border Collies

Day Blindness

Identified in Labrador Retrievers

Primary Open Angle Glaucoma and Primary Lens Luxation

Identified in Chinese Shar-Peis

Goniodysgenesis and Glaucoma, Pectinate Ligament Dysplasia, PLD

Identified in Border Collies

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Cystinuria Type II-B

Identified in Miniature Pinschers

Urate Kidney & Bladder Stones

Identified in Dalmatians and Labrador Retrievers

Familial Nephropathy

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neuronal Ceroid Lipofuscinosis 5, NCL 5

Identified in Border Collies

Shar-Pei Autoinflammatory Disease, SPAID, Shar-Pei Fever

Identified in Chinese Shar-Peis

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Labrador Retrievers

Narcolepsy

Identified in Labrador Retrievers

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Sensory Neuropathy

Identified in Border Collies

Ullrich-like Congenital Muscular Dystrophy

Identified in Labrador Retrievers

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels and Labrador Retrievers

Myotonia Congenita

Identified in Border Collies

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Cobalamin Malabsorption

Identified in Border Collies

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Raine Syndrome

Identified in Border Collies

Intervertebral Disc Disease (Type I)

Identified in Cocker Spaniels

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Bonnie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B28

Map

B1

Bonnie’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B28

Bonnie’s Haplotype

Part of the large B1 haplogroup, we have spotted this haplotype frequently in Cocker Spaniels, Pomeranians, Cavalier King Charles Spaniels, and village dogs in Liberia and Namibia.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Bonnie inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Bonnie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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