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Blue

Mixed Ancestry

“He's an anxious boy, but he loves playtime and cuddling. He is a snack-aholic with a big sweet tooth. Candy must be kept in high locations at all times. He loves exploring, even if it gets him into trouble. Sunbathing in the yard or on the porch is an ideal way to spend an afternoon for Blue.”

This dog has been viewed and been given 2 wags

Genetic Breed Result

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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American Eskimo Dog

American Eskimo Dogs belong to the spitz family and they actually came from Germany. They got their start in American circuses due to their intelligence. Today, Eskies make wonderful family pets.

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Dogs Like Blue

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Discover dogs who share a similar breed mix to Blue. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Beagle
Siberian Husky
German Shepherd Dog
American Eskimo Dog

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Here’s what Blue’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Blue’s breed mix.
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Health Summary

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Blue is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

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Blue inherited one copy of the variant we tested

How to interpret this result

Blue has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Musladin-Lueke Syndrome, MLS

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Blue inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Blue’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Blue is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Musladin-Lueke Syndrome, MLS?

This condition causes abnormally strong connections between the structural proteins that provide strength and integrity to tissues like the skin and skeletal muscle, as well as the protective tissue sheaths of the bones and central nervous system.

ALT Activity

No result

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Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in American Eskimo Dogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Pyruvate Kinase Deficiency

Identified in Beagles

Progressive Retinal Atrophy, prcd

Identified in American Eskimo Dogs

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Day Blindness

Identified in German Shepherd Dogs

Primary Open Angle Glaucoma

Identified in Beagles

Primary Lens Luxation

Identified in American Eskimo Dogs

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

GM1 Gangliosidosis

Identified in Siberian Huskies

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in American Eskimo Dogs, German Shepherd Dogs, and more

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Blue’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C25

Map

C1

Blue’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C25

Blue’s Haplotype

Part of the C1 haplogroup, this haplotype has been spotted in village dogs in Peru and Namibia. Among breeds, it occurs most frequently in Doberman Pinschers, but has also been detected in German Shepherd Dogs and Labrador Retrievers.

The C1 maternal line is commonly found in Jackals.

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Through Blue’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

D

Haplotype

H7

Map

D

Blue’s Haplogroup

The D paternal lineage is very common in well-known populations of dogs. Breeds belonging to the D lineage likely have direct male ancestors that can be traced all the way back to the origin of domestic dogs themselves! One popular breed that commonly sports a D lineage is the Boxer. Boxers were developed in the late 19th century from Mastiff dogs, so it is no surprise that D is well represented among Mastiffs, Bulldogs, as well as Terriers. Intriguingly, D is also found among Lhasa Apsos, an ancient Tibetan breed, and Afghan Hounds. While the presence of this lineage in Polynesia or the New World can be chalked up to interbreeding with European dogs brought during voyages of discovery or later settlement, D is also well represented among village dog populations in the Middle East and Africa. If the fact that we find dogs bearing a D lineage in the Middle East (not to mention the large amount of diversity among Middle Eastern D lineage males) is any indication of ancient residence in that region, then the presence among Oceanian village dogs is peculiar. Rather, it may be that D is part of a broader Eurasian group of ancient paternal lineages which disappeared from the eastern portion of its original range, persisting in the island of New Guinea as well as West Asia and Africa. With the rise of Mastiff breeds, the D lineage received a new life as it became common among many types of working dogs.

H7

Blue’s Haplotype

Part of the D haplogroup, this common haplotype has been found in French Bulldogs, Afghan Hounds, Bull Terriers, and village dogs spanning from South America to Africa and into the South Pacific.

The D paternal lineage is common in Boxers.

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