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“Nisse”
Wild Clover’s Farmhouse Sprite

Schapendoes

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Genetic Breed Result

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Schapendoes

The Schapendoes is a long-coated, medium-sized breed from the Netherlands. Originally bred as a herding dog, the Schapendoes is intelligent and highly trainable, making them excellent family pets.

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Changes to this dog’s profile
  • On 2/8/2023 changed name from "Biscuit" to "Wild Clover’s Farmhouse Sprite"

Health Summary

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Nisse inherited two variants that you should learn more about.

Urate Kidney & Bladder Stones

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Nisse inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Nisse is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Urate Kidney & Bladder Stones?

This condition causes kidney and bladder stones composed of urate. In most dogs, uric acid is converted to allantoin, an inert substance that is then excreted in the urine. Dogs with HUU have defects in the pathway that converts uric acid to allantoin. As such, uric acid builds up, crystallizes and forms urate stones in the kidney and bladder. Uric acid is an intermediate of purine metabolism. While hyperuricemia in other species (including humans) can lead to painful conditions such as gout, dogs do not develop systemic signs of hyperuricemia.

Dilated Cardiomyopathy, DCM2

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Nisse inherited one copy of the variant we tested

What does this result mean?

Research indicates that this genetic variant is not likely to increase the risk that Nisse will develop this condition.

Scientific Basis

Dogs with Nisse’s breed have been included in research studies or have had follow-up by our experts that indicate that this genetic variant is not likely to increase the risk of Nisse developing clinical disease.

Impact on Breeding

This genetic result should not be the primary factor in your breeding decisions.

What is Dilated Cardiomyopathy, DCM2?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Clinical Tools

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Nisse’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

C1

Haplotype

C38

Map

C1

Wild Clover’s Farmhouse Sprite’s Haplogroup

Congratulations, C1 is a very exotic female lineage! It is more closely associated with maternal lineages found in wolves, foxes and jackals than with other dog lineages. So it seems dogs in this group have a common male dog ancestor who, many thousands of years ago, mated with a female wolf! This is not a common lineage in any breed, though a good number of German Shepherds and Doberman Pinchers are C1. It is also found in breeds as diverse as Peruvian Inca Orchids and Pekingese; it is rarely found amongst Labrador Retrievers, Border Collies, Siberian Huskies, or Cocker Spaniels. Despite its fascinating origins, it is widely distributed around the globe, and even shows up frequently among Peruvian village dogs. It almost certainly survived at low frequency in Europe for millennia and then was dispersed outside of Europe by colonialism, though not as successfully as some other lineages.

C38

Wild Clover’s Farmhouse Sprite’s Haplotype

Part of the C1 haplogroup, this haplotype occurs most frequently in Doberman Pinschers and Black Russian Terriers.

Some other Embark dogs with this haplotype:

The C1 maternal line is commonly found in Jackals.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Nisse inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Nisse is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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