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Biggie Smalls

Mixed Ancestry

“Biggie suffers separation anxiety even with 4 brothers and sisters keeping him company. He is a very smart dog and learned the basics within 2 months. He also learns by watching the humans. He can unlatch and open baby gate, turn on ceiling fan, even sits like us. He wasn’t taught these things but picked it up on his own. He loves water and his paws are webbed. He sleeps on his back all the time. He is very energetic”

Current Location

Westminster, Colorado, USA

This dog has been viewed and been given 16 wags

Genetic Breed Result

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Belgian Malinois

The Belgian Malinois is an impressive working dog. These guys have become a staple within the military and the police force due to their intelligence and drive. They can make wonderful companions as long as they are thoroughly exercised.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Rottweiler

Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.

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Dogs Like Biggie Smalls

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Discover dogs who share a similar breed mix to Biggie Smalls. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Belgian Malinois
American Pit Bull Terrier
Rottweiler

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Here’s what Biggie Smalls’s family tree may have looked like.
While there may be other possible configurations of his family’s relationships, this is the most likely family tree to explain Biggie Smalls’s breed mix.
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Health Summary

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Biggie Smalls inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Biggie Smalls inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Biggie Smalls’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Biggie Smalls is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Degenerative Myelopathy, DM

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Biggie Smalls inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Biggie Smalls’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Biggie Smalls is unlikely to develop this condition due to this variant because he only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Biggie Smalls inherited one copy of the variant we tested

Why is this important to your vet?

Biggie Smalls has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Biggie Smalls has this genotype, as ALT is often used as an indicator of liver health and Biggie Smalls is likely to have a lower than average resting ALT activity. As such, an increase in Biggie Smalls’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2

Identified in American Pit Bull Terriers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in Belgian Malinois

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Juvenile Laryngeal Paralysis and Polyneuropathy

Identified in Rottweilers

Spongy Degeneration with Cerebellar Ataxia 1

Identified in Belgian Malinois

Spongy Degeneration with Cerebellar Ataxia 2

Identified in Belgian Malinois

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

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Other Body Features

Other Body Features

Body Size

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Through Biggie Smalls’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

A361/409/611

Map

A1b

Biggie Smalls’s Haplogroup

This female lineage was very likely one of the original lineages in the wolves that were first domesticated into dogs in Central Asia about 15,000 years ago. Since then, the lineage has been very successful and travelled the globe! Dogs from this group are found in ancient Bronze Age fossils in the Middle East and southern Europe. By the end of the Bronze Age, it became exceedingly common in Europe. These dogs later became many of the dogs that started some of today's most popular breeds, like German Shepherds, Pugs, Whippets, English Sheepdogs and Miniature Schnauzers. During the period of European colonization, the lineage became even more widespread as European dogs followed their owners to far-flung places like South America and Oceania. It's now found in many popular breeds as well as village dogs across the world!

A361/409/611

Biggie Smalls’s Haplotype

Part of the A1b haplogroup, this haplotype occurs most frequently in German Shepherd Dogs, Poodles, and Shiloh Shepherds.

A1b is the most common haplogroup found in German Shepherds.

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Through Biggie Smalls’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.59

Map

A1a

Biggie Smalls’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.59

Biggie Smalls’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in European village dogs.

Dogs with A1a lineage travelled during European Colonial times.

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