What is Embark?

Betty

Mixed Breed

“Betty is the best dog!”

This dog has been viewed 216 times and been given 1 wag

Genetic Breed Result

Learn how it’s done

Mixed Breed

27.7% Beagle
19.6% American Pit Bull Terrier
14.9% American Foxhound
8.4% German Shepherd Dog
7.6% Golden Retriever
7.4% Chinese Shar-Pei
6.4% American Staffordshire Terrier
8.0% Supermutt

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from this distant ancestor:

Beagle Beagle
The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.
Learn More
American Pit Bull Terrier American Pit Bull Terrier
Few dogs are more recognizable than the American Pit Bull Terrier. While they originated in the British Isles and are descendants of the Mastiff-type dogs introduced to England in antiquity, the American Pit Bull Terrier was brought over to the United States by English immigrants in the 1800s. They quickly became one of the most popular and widespread breeds there.
Learn More
American Foxhound American Foxhound
American Foxhounds, the American cousin of the English Foxhounds, are a lucky breed because their history and ancestry are well documented. They came over to the New World in 1650 with a man named Robert Brooke, who sailed from England to Crown Colony in North America (now modern day Maryland and Virginia). This pack of hunting dogs, beloved by the Brooke Family for hundreds of years, evolved to become the American Foxhound. The Brooke hounds were likely mixed with French hounds that were also brought to the Americas, and it was this mix of European breeds that eventually gave us our beloved American Foxhound.
Learn More
German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence.
Learn More
Golden Retriever Golden Retriever
Developed as an ideal hunting retriever, the Golden Retriever's eagerness to please and friendliness has made them an extremely popular family pet.
Learn More
Chinese Shar-Pei Chinese Shar-Pei
Also known as the Shar Pei or Chinese Fighting Dog, even though the Chinese Shar-Pei is the 134th breed recognized by the American Kennel Club, the dog breed has been around for hundreds of years. He was developed to guard, hunt, herd, and later, fight, and is known for his characteristic short, bristly coat, loose, wrinkled skin, and devotion to his family. Today, the Shar-Pei mostly enjoys life as a beloved companion.
Learn More
American Staffordshire Terrier American Staffordshire Terrier
American Staffordshire Terrier's are powerul but playful dogs, that are both loyal and affectionate with their owners.
Learn More
Start a conversation! Log in to send a direct message to this dog’s owner.

Genetic Stats

Wolfiness: 0.8 % MEDIUM Learn More
Predicted Adult Weight: 27 lbs Learn More
Genetic Age: 45 human years Learn More

Explore other Embark dogs who have breed mixes that are similar to Betty’s.
A Mix Match of 100 means they are the exact same breed mix!

Breed Mix Matches

DNA Breed Origins

What’s this?
Breed colors:
Beagle
American Pit Bull Terrier
American Foxhound
German Shepherd Dog
Golden Retriever
Chinese Shar-Pei
American Staffordshire Terrier
Supermutt

Explore:

Family tree

Health

Traits

Maternal Haplotype

Paternal Haplotype

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Beagle mix Mixed Beagle American Foxhound / Chinese Shar-Pei mix American Pit Bull Terrier / American Staffordshire Terrier mix Golden Retriever / German Shepherd Dog mix Beagle Beagle American Foxhound Chinese Shar-Pei mix American Pit Bull Terrier American Staffordshire Terrier mix Golden Retriever mix German Shepherd Dog mix
Explore by tapping the parents and grandparents.

Our algorithms predict this is the most likely family tree to explain Betty’s breed mix, but this family tree may not be the only possible one.

Explore:

Health

Traits

Maternal Haplotype

Paternal Haplotype

Summary

0
AT RISK
1
CARRIER
164
CLEAR
Tap above or scroll down to see more

Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood chemistry panels and is known to be a se…
Betty has two normal alleles at ALT.

Not At Risk

Good news! Betty did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Betty does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Betty’s diagnosis and treatment if she gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Carrier for 1 genetic condition

Betty is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?

Betty has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Betty ever has children.

Condition List

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Common Conditions

Good news! Betty tested clear for 30 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Betty.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in Beagles, American Foxhounds, but not Betty.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in German Shepherd Dogs, but not Betty.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies represent a broad category of diseases that affect blood clotting, which can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies a…

Seen in German Shepherd Dogs, but not Betty.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Betty.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Beagle Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Beagles, but not Betty.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Golden Retrievers, but not Betty.

Golden Retriever Progressive Retinal Atrophy 2
(TTC8)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Golden Retrievers, but not Betty.

Progressive Retinal Atrophy - crd1
(PDE6B)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Betty.

Progressive Retinal Atrophy - crd2
(IQCB1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Betty.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Betty.

Glaucoma
Primary Open Angle Glaucoma (ADAMTS10 Exon 17)
Eyes

A disease that affects humans and dogs alike, this is an adult onset, medically manageable condition that causes high intraocular pressure (IOP). Left untreated, it can l…

Seen in Beagles, but not Betty.

Hyperuricosuria and Hyperuricemia or Urolithiasis
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Betty.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Betty.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Betty.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Betty.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia - NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in American Pit Bull Terriers, American Staffordshire Terriers, but not Betty.

Neuronal Ceroid Lipofuscinosis
(CLN5 Exon 4 Variant 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Golden Retrievers, but not Betty.

Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration
(SPTBN2)
Brain and Spinal Cord

Known as the most primordial part of the brain, the cerebellum fine tunes motor signals from the brain to the muscles, allowing for balance and coordination. Symptoms of …

Seen in Beagles, but not Betty.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Beagles, American Pit Bull Terriers, American Foxhounds, German Shepherd Dogs, Golden Retrievers, Chinese Shar-Peis, American Staffordshire Terriers, but not Betty.

Fetal-Onset Neonatal Neuroaxonal Dystrophy
(MFN2)
Brain and Spinal Cord

This group of diseases center around the neuronal axon, a specialized cellular structure that helps our nervous systems relay information across great distances. Remember…

Seen in Beagles, but not Betty.

Muscular Dystrophy
Muscular Dystrophy (DMD Golden Retriever Variant)
Muscular

Characterized by non-painful muscle weakness and wasting, early diagnosis and supportive treatment can slow the pace of this progressive muscle disease. All known mutatio…

Seen in Golden Retrievers, but not Betty.

Hypocatalasia, Acatalasemia
(CAT)
Metabolic

This condition causes no ill effects in the majority of dogs; however, some dogs can suffer from mouth ulcers leading to difficulty eating and increased susceptibility to…

Seen in Beagles, but not Betty.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in Beagles, American Pit Bull Terriers, American Foxhounds, German Shepherd Dogs, Golden Retrievers, Chinese Shar-Peis, American Staffordshire Terriers, but not Betty.

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption
(CUBN Exon 8)
Gastro-intestinal

This is a treatable gastrointestinal disease where dogs cannot absorb cobalamin, often causing them to be runty with poor energy levels. Cobalamin is required for synthes…

Seen in Beagles, but not Betty.

Dystrophic Epidermolysis Bullosa
(COL7A1)
Skin & Connective Tissues

This skin disorder gives affected dogs skin that stretches and tears easily; affected dogs must be monitored closely and treated promptly for any injuries. It arises from…

Seen in Golden Retrievers, but not Betty.

Ichthyosis
(PNPLA1)
Skin & Connective Tissues

This skin disorder gets its name from the thick, darkly pigmented scales of skin (“ichthys” is Greek for “fish”) that affected dogs display on their noses, paw pads, and …

Seen in Golden Retrievers, but not Betty.

Musladin-Lueke Syndrome
(ADAMTSL2)
Skin & Connective Tissues

First characterized in the Beagle, condition causes abnormally strong connections between cells of the skin and muscle and can cause gait abnormalities and pressure sores…

Seen in Beagles, but not Betty.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A2)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Beagles, but not Betty.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A1)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Golden Retrievers, but not Betty.

Other Conditions: Clear of 134

Betty is clear of 134 other genetic diseases that Embark tests for.

Explore:

Family tree

Traits

Maternal Haplotype

Paternal Haplotype

Jump to:

Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Ee
K Locus (Dominant Black)
kyky
A Locus (Agouti, Sable)
awat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NI
Body Size - IGF1R
GG
Body Size - STC2
AA
Body Size - GHR (E195K)
GA
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

Explore:

Family tree

Health

Maternal Haplotype

Paternal Haplotype

Through Betty’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Betty’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Betty’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Explore:

Family tree

Health

Traits

Paternal Haplotype

This 'Paternal Haplotype' tab is for deep ancestral lineage going back thousands of years.

For recent ancestry—"What breeds did my dog inherit from her mom and dad?"—please refer to the Breed, Family Tree, or Summary tab.

The Paternal Haplotype refers to a dog’s deep ancestral lineage stretching back thousands of years, before there were any distinct breeds of dog. We determine the Paternal Haplotype by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Betty is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Explore:

Family tree

Health

Traits

Maternal Haplotype