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“Bruschi”
BB BEER NEVER BROKE MY HEART LIGORJANA

Tibetan Mastiff

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Place of Birth

Warsaw, Masovian Voivodeship, Poland

Current Location

Pueblo West, Colorado, USA

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Registration

American Kennel Club (AKC):

Genetic Breed Result

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Tibetan Mastiff

The Tibetan Mastiff is one giant fluff ball. This ancient breed has been guarding and protecting their owners for thousands of years. This intelligent and indepent dog loves to be around the people they care about.

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Health Summary

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Bruschi has one variant that you should let your vet know about.

ALT Activity

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Bruschi inherited both copies of the variant we tested

Why is this important to your vet?

Bruschi has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Bruschi's ALT activity above their current, healthy, ALT activity. As an increase above Bruschi’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Traits

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Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

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Body Size

Performance

Performance

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Through Bruschi’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2

Haplotype

A448

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A2

BB BEER NEVER BROKE MY HEART LIGORJANA’s Haplogroup

A2 is a very ancient maternal line. Most likely it was one of the major female lines that contributed to the very first domesticated dogs in Central Asia about 15,000 years ago. Some of the line stayed in Central Asia to the present day, and frequently appear as Tibetan Mastiffs and Akitas. Those that escaped the mountains of Central Asia sought out other cold spots, and are now found among Alaskan Malamutes and Siberian Huskies. This lineage is also occasionally found in several common Western breeds, such as German Shepherds and Labrador Retrievers. Curiously, all New Guinea Singing Dogs descend from this line. These are an ancient and very interesting breed found in the mountains of Papua New Guinea. Unfortunately, they are now endangered. They are closely related to the Australian dingo, so you could say its cousins are dingos! This line is also common in village dogs in Southeast and East Asia. Unlike many other lineages, A2 did not spread across the whole world, probably because it did not have the opportunity to hitch its wagon to European colonialism - or because these dogs just prefer hanging out in mountains, tundras, islands, and other hard-to-reach places!

A448

BB BEER NEVER BROKE MY HEART LIGORJANA’s Haplotype

Part of the A2 haplogroup, the A448 haplotype occurs most commonly in McNabs. It's a rare find!

Some other Embark dogs with this haplotype:

Dingos commonly possess this haplogroup.

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Through Bruschi’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B

Haplotype

H15.8

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B

BB BEER NEVER BROKE MY HEART LIGORJANA’s Haplogroup

B is a relatively rare paternal line that has only recently started to expand. The dominant lineage among the ancient Shih Tzu breed, it is also found among Tibetan Spaniels. Outside of these two breeds, B seems to be a particularly common paternal line among the village dogs of India and Southeast Asia, though it is found as far afield as Africa and down into Oceania. Considering that it is particularly diverse in northern India, it could be that this lineage hung out mostly in South Asia after the expansion of domestic dogs from Central Asia. Because it is present in Mongolia as well, it may not be surprising that ancient East Asian dog breeds are also part of this lineage. Alternatively, perhaps males representing this lineage headed north out of southern Eurasia, which eventually gave rise to the Shih Tzu and may have inspired stylistic representations of lions in ancient China!

H15.8

BB BEER NEVER BROKE MY HEART LIGORJANA’s Haplotype

Part of the B haplogroup, this haplotype has been found mostly in village dogs in south Asia, specifically in India and Nepal.

Some other Embark dogs with this haplotype:

The B Haplogroup is most commonly found the adorable Shih Tzu breed.

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