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Axel

Mixed Breed

“Axel loves to take a nap next to a family member and have his body touching you. He wants to be in the same room with people and loves to play with his toys. He like to rest in the superman pose. When someone from the family comes home he wags his tail and shakes his body.”

Current Location
Michigan, USA
From
humane society near Sterling Heights, MI, USA

This dog has been viewed 945 times and been given 23 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

49.2% Staffordshire Terrier
15.9% Rottweiler
12.4% German Shepherd Dog
9.6% Boxer
6.9% Bullmastiff
6.0% Chow Chow
Staffordshire Terrier Staffordshire Terrier
Staffordshire Terriers, sometimes referred to as "pit bull" type, are intelligent and trainable dogs. They can have a lot of energy and are often great canine athletes!
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Rottweiler Rottweiler
Originally used for driving cattle and protecting valuable convoys, Rottweilers are now popular family pets as well as guard, police and military dogs.
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German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.
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Boxer Boxer
Developed in Germany, the Boxer is a popular family dog-patient, loyal and smart-requiring lots of exercise and proper training.
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Bullmastiff Bullmastiff
The Bullmastiff is an enormous fellow that loves to sleep and drool. They were developed in England as guard dogs, but were bred not to bite. Today, they make wonderful family dogs due to their gentle nature.
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Chow Chow Chow Chow
This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.
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Genetic Stats


Wolfiness

0.3 % LOW Learn More

Predicted Adult Weight

59 lbs Learn More

Genetic Age
31 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Axel’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Staffordshire Terrier
Rottweiler
German Shepherd Dog
Boxer
Bullmastiff
Chow Chow

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Staffordshire Terrier mix Staffordshire Terrier mix Staffordshire Terrier Rottweiler / Bullmastiff mix Staffordshire Terrier German Shepherd Dog / Boxer mix Staffordshire Terrier Staffordshire Terrier Rottweiler Bullmastiff mix Staffordshire Terrier Staffordshire Terrier German Shepherd Dog Boxer mix

Our algorithms predict this is the most likely family tree to explain Axel’s breed mix, but this family tree may not be the only possible one.

Summary

0
AT RISK
1
CARRIER
161
CLEAR
Tap above or scroll down to see more

Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Axel has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Axel has this genotype, as ALT is often used as an indicator of liver health and Axel is likely to have a lower than average resting ALT activity. As such, an increase in Axel’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Axel did not test positive for any of the genetic conditions that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Axel’s diagnosis and treatment if he gets sick in the future.

Carrier for
1 genetic condition

Axel is a carrier for 1 of the genetic diseases that Embark tests for.
What does Carrier mean?

Axel has inherited a recessive allele for a genetic trait or mutation. This is not enough to cause symptoms of the disease, but is important to bear in mind if Axel ever has children.

Condition List

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Common Conditions

Good news! Axel tested clear for 20 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Axel.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 10, Boxer Variant)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Boxers, but not Axel.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Axel.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Axel.

Canine Leukocyte Adhesion Deficiency Type III, LAD3
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Axel.

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Seen in Boxers, but not Axel.

Canine Elliptocytosis
(SPTB Exon 30)
Blood

A benign disease that affects red blood cell shape, elliptocytosis rarely causes symptoms. Upon examination of a blood smear, however, affected dogs have elongated, oval …

Seen in Chow Chows, but not Axel.

Progressive Retinal Atrophy, crd1
(PDE6B)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Staffordshire Terriers, but not Axel.

Progressive Retinal Atrophy, crd2
(IQCB1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Staffordshire Terriers, but not Axel.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Axel.

Autosomal Dominant Progressive Retinal Atrophy
(RHO)
Eyes

This rapidly progressive form of PRA can be triggered by high intensity light exposure. In fact, the light intensity used in a normal veterinary ophthalmological exam can…

Seen in Bullmastiffs, but not Axel.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. CMR is typically only identified when a vet examines the eye which, in dogs with C…

Seen in Bullmastiffs, but not Axel.

Hereditary Cataracts, Early-Onset Cataracts, Juvenile Cataracts
(HSF4 Exon 9 Boston Terrier Variant)
Eyes

One of the leading causes of blindness in dogs (and humans!), cataracts are a progressive disease of the lens that causes functional blindness, but can be surgically corr…

Seen in Staffordshire Terriers, but not Axel.

Hyperuricosuria and Hyperuricemia or Urolithiasis, HUU
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in Staffordshire Terriers, German Shepherd Dogs, but not Axel.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Axel.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis, RCND
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Axel.

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Axel.

Neuronal Ceroid Lipofuscinosis 1, Cerebellar Ataxia, NCL-A
(ARSG Exon 2)
Multisystem

This form of lysosomal storage disease can cause juvenile to adult-onset neurologic signs, depending on the affected gene. While lipofuscin is commonly observed in the ti…

Seen in Staffordshire Terriers, but not Axel.

Degenerative Myelopathy, DM
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in German Shepherd Dogs, Boxers, but not Axel.

L-2-Hydroxyglutaricaciduria, L2HGA
(L2HGDH)
Brain and Spinal Cord

Currently there is no definitive treatment for L2HGA; rather, the condition is managed with anti-seizure and anti-anxiety medications. A rare metabolic disorder, this can…

Seen in Staffordshire Terriers, but not Axel.

Other Conditions:
Clear of 141

Axel is clear of 141 other genetic conditions that Embark tests for.

Through Axel’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Axel’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Axel’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

Through Axel’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A2b

Haplotype

Hc.9

Map

A2b

Axel’s Haplogroup

A2b appears to have split a few times in succession, which means that some of the Central Asian male ancestors of this lineage went their separate ways before their respective Y chromosomes made their rounds. There is not much diversity in this lineage, meaning that it has only begun to take off recently. Two iconic breeds, the Dachshund and Bloodhound, represent this lineage well. Over half of Rottweilers are A2b, as are the majority of Labrador Retrievers and Cavalier King Charles Spaniels. While A2a is restricted mostly to East Asia, this paternal line is also found among European breeds.

Hc.9

Axel’s Haplotype

Part of the A2b haplogroup, this haplotype is found in village dogs spanning South America, Africa, and the South Pacific. Among the 11 breeds we have spotted it in, the most frequent occurrences are in Dachshund, Bloodhound, American Eskimo Dog, and Jack Russell Terrier.

Some other Embark dogs with this haplotype:

A2b is found in the Daschund breed.