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“Ciri”
Avalon Witch Hazel

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“Ciri was the last born, and smallest of our Apothecary Litter pups. She also has stayed with us to hopefully one day continue our breeding program.”

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@avalon.tamaskan

This dog has been viewed and been given 6 wags

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Genetic Stats

Predicted Adult Weight

59 lbs

Genetic Age
16 human years

Based on the date of birth provided

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Health Summary

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Ciri has one variant that you should let your vet know about.

ALT Activity

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Ciri inherited one copy of the variant we tested

Why is this important to your vet?

Ciri has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Ciri has this genotype, as ALT is often used as an indicator of liver health and Ciri is likely to have a lower than average resting ALT activity. As such, an increase in Ciri’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Factor VII Deficiency (F7 Exon 5)

Identified in Alaskan Malamutes

Hemophilia A (F8 Exon 11, German Shepherd Variant 1)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Hemophilia A (F8 Exon 1, German Shepherd Variant 2)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Platelet Factor X Receptor Deficiency, Scott Syndrome (TMEM16F)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Karelian Bear Dogs

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Day Blindness (CNGB3 Deletion, Alaskan Malamute Variant)

Identified in Alaskan Malamutes and Siberian Huskies

Day Blindness (CNGA3 Exon 7, German Shepherd Variant)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Urate Kidney & Bladder Stones (SLC2A9)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Primary Ciliary Dyskinesia, PCD (NME5, Alaskan Malamute Variant)

Identified in Alaskan Malamutes

Anhidrotic Ectodermal Dysplasia (EDA Intron 8)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in German Shepherd Dogs and Saarloos Wolfdogs

Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)

Identified in Alaskan Malamutes

Chondrodystrophy (ITGA10, Norwegian Elkhound and Karelian Bear Dog Variant)

Identified in Karelian Bear Dogs

Additional Genetic Conditions

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