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Autumn

Mixed Ancestry

“I adopted Autumn from a town shelter on 6/11/17. I was told she was 10 months but I think she was a bit younger. She was 17 lbs then now she's 28-ish. She is a huge love bug with her humans but is standoffish with outsiders & very protective of the home.”

Instagram tag
@linightowl

Current Location

New York, USA

From

Brookhaven Animal Shelter, Horseblock Road, Brookhaven, NY, USA

This dog has been viewed and been given 34 wags

Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Rat Terrier

The Rat Terrier is an American dog breed with a background as a farm dog and hunting companion.

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American Pit Bull Terrier

The American Pit Bull Terrier originated in the British Isles and descends from the Mastiff-type dogs introduced to England in antiquity. The breed was brought over to the United States by English immigrants in the 1800s, and quickly became one of the most popular and widespread breeds there.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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Labrador Retriever

The Labrador Retriever was bred for hunting and excelled in retrieving game after it was shot down. Known for its gentle disposition and loyalty, the Labrador Retriever has become a favorite of families and breeders alike.

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Shih Tzu

This ancient breed is the perfect lapdog. Sweet and easygoing, they want nothing more than to be close to their humans.

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Dogs Like Autumn

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Discover dogs who share a similar breed mix to Autumn. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Cocker Spaniel
Rat Terrier
American Pit Bull Terrier
Pomeranian
Boxer
Labrador Retriever
Shih Tzu
Supermutt

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Here’s what Autumn’s family tree may have looked like.
Autumn
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Cocker Spaniel mix Rat Terrier / Labrador Retriever mix American Pit Bull Terrier / Boxer mix Cocker Spaniel Pomeranian mix Rat Terrier Labrador Retriever mix American Pit Bull Terrier Boxer mix Cocker Spaniel Cocker Spaniel Pomeranian Mixed
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Autumn’s breed mix.
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Health Summary

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Autumn is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Autumn inherited one copy of the variant we tested

How to interpret this result

Autumn has one copy of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Progressive Retinal Atrophy, prcd

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Autumn inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Autumn’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Autumn is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, prcd?

PRA-prcd is a retinal disease that causes progressive, non-painful vision loss. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of rod cells, leading to night blindness before day blindness.

ALT Activity

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Autumn inherited both copies of the variant we tested

Why is this important to your vet?

Autumn has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Autumn's ALT activity above their current, healthy, ALT activity. As an increase above Autumn’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Hemophilia A

Identified in Boxers

Canine Elliptocytosis

Identified in Labrador Retrievers

Prekallikrein Deficiency

Identified in Shih Tzus

Pyruvate Kinase Deficiency

Identified in Labrador Retrievers

Progressive Retinal Atrophy, rcd3

Identified in Pomeranians

Golden Retriever Progressive Retinal Atrophy 2, GR-PRA2

Identified in Labrador Retrievers

Progressive Retinal Atrophy, crd1

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd2

Identified in American Pit Bull Terriers

Progressive Retinal Atrophy, crd4/cord1

Identified in Labrador Retrievers

Day Blindness

Identified in Labrador Retrievers

Primary Lens Luxation

Identified in Rat Terriers

Macular Corneal Dystrophy, MCD

Identified in Labrador Retrievers

Urate Kidney & Bladder Stones

Identified in American Pit Bull Terriers, Labrador Retrievers, and more

Familial Nephropathy

Identified in Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Pit Bull Terriers

Alexander Disease

Identified in Labrador Retrievers

Degenerative Myelopathy, DM

Identified in Boxers and Labrador Retrievers

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Pit Bull Terriers

Narcolepsy

Identified in Labrador Retrievers

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Centronuclear Myopathy, CNM

Identified in Labrador Retrievers

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels and Labrador Retrievers

X-Linked Myotubular Myopathy

Identified in Labrador Retrievers

Congenital Myasthenic Syndrome, CMS

Identified in Labrador Retrievers

Hereditary Nasal Parakeratosis, HNPK

Identified in Labrador Retrievers

Hereditary Vitamin D-Resistant Rickets

Identified in Pomeranians

Skeletal Dysplasia 2, SD2

Identified in Labrador Retrievers

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Autumn’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Autumn’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Autumn’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Autumn inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Autumn is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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