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“Sonia”
AUS CH NyaStar’s Hawaiian Heat Down Under

Irish Red and White Setter

No bio has been provided yet

Place of Birth

Hawaii, USA

Current Location

Minneapolis, Minnesota, USA

From

Australia

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Registration

American Kennel Club (AKC): SR86939403

Genetic Breed Result

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Irish Red and White Setter

Irish Red and White Setters are exceptional gun dogs and have been helping their masters hunt birds for centuries.

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Health Summary

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Sonia has one variant that you should let your vet know about.

ALT Activity

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Sonia inherited one copy of the variant we tested

Why is this important to your vet?

Sonia has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Sonia has this genotype, as ALT is often used as an indicator of liver health and Sonia is likely to have a lower than average resting ALT activity. As such, an increase in Sonia’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Irish Red and White Setters

Canine Leukocyte Adhesion Deficiency Type I, CLAD I (ITGB2, Setter Variant)

Identified in Irish Red and White Setters

Progressive Retinal Atrophy, rcd1 (PDE6B Exon 21, Irish Setter Variant)

Identified in Irish Red and White Setters

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

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Through Sonia’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A163

Map

A1e

AUS CH NyaStar’s Hawaiian Heat Down Under’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A163

AUS CH NyaStar’s Hawaiian Heat Down Under’s Haplotype

Part of the large A1e haplogroup, this haplotype occurs most commonly in German Shorthaired Pointers. It’s a rare find!

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Sonia inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Sonia is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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