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“Wyatt”
Aspens Huntsville Nights

Teddy Roosevelt Terrier

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Place of Birth

USA

Current Location

Bremen, Alabama, USA

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Registration

N/A : UKC Reg# P888157
Microchip: 933000320129715

Genetic Breed Result

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Teddy Roosevelt Terrier

The Teddy Roosevelt Terrier is an American breed developed to be both effective ratters and devoted family companions. While many Teddies are loving pets, they’re a versatile breed also at home competing in barn hunt, agility, and more.

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Health Summary

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Wyatt is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Primary Lens Luxation

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Wyatt inherited one copy of the variant we tested

How to interpret this result

Wyatt has one copy of a variant in the ADAMTS17 gene and is at some risk for developing PLL. This variant is known to have an additive effect, so while dogs with one copy of the variant like Wyatt have a higher risk than dogs with two healthy alleles at ADAMTS17, their risk is much lower than a dog with two copies of the variant. Actual risk associated with having one copy of this variant appears to vary in a breed-specific manner. A study published by Gould et al 2011 supports that Tibetan Terriers with one copy of the variant have minimal risk of developing PLL, whereas this risk can range from 2-20% in other terrier breeds. Please consult with your veterinarian to discuss the best ways to monitor Wyatt's eyes and vision.

What is Primary Lens Luxation?

PLL occurs when the lens spontaneously detaches from its normal residence within the pupil, leading to reduced visual acuity. Anterior lens luxation is when the lens falls forward and posterior lens luxation is when the lens falls backwards in the eye.

ALT Activity

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Wyatt inherited one copy of the variant we tested

Why is this important to your vet?

Wyatt has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Wyatt has this genotype, as ALT is often used as an indicator of liver health and Wyatt is likely to have a lower than average resting ALT activity. As such, an increase in Wyatt’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Through Wyatt’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A11a/419

Map

A1d

Aspens Huntsville Nights’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A11a/419

Aspens Huntsville Nights’s Haplotype

Part of the A1d haplogroup, this haplotype occurs most frequently in Yorkshire Terriers, Old English Sheepdogs, and Miniature Schnauzers.

Some other Embark dogs with this haplotype:

The vast majority of Rottweilers have the A1d haplogroup.

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Through Wyatt’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.48

Map

A1a

Aspens Huntsville Nights’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.48

Aspens Huntsville Nights’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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