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Asirpa

Hokkaido

“She is a foundation bitch registered with AKC FSS.”

Place of Birth

Japan

Current Location

Dover, Ohio, USA

From

Japan

This dog has been viewed and been given 1 wag

Registration

American Kennel Club (AKC): WS61377701

Genetic Breed Result

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Hokkaido

Well known for their loyalty, bravery, and intelligence, Hokkaidos are breed of dog are prized in Japan.

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Health Summary

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Asirpa inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Congenital Macrothrombocytopenia

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Asirpa inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Asirpa’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Asirpa is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Congenital Macrothrombocytopenia?

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets.

ALT Activity

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Asirpa inherited both copies of the variant we tested

Why is this important to your vet?

Asirpa has two copies of a variant in the GPT gene and is likely to have a lower than average baseline ALT activity. ALT is a commonly used measure of liver health on routine veterinary blood chemistry panels. As such, your veterinarian may want to watch for changes in Asirpa's ALT activity above their current, healthy, ALT activity. As an increase above Asirpa’s baseline ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Collie Eye Anomaly (NHEJ1)

Identified in Hokkaidos

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Asirpa’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A388

Map

A1a

Asirpa’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A388

Asirpa’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs most frequently in Staffordshire Terriers, Labrador Retrievers, and English Bulldogs.

Shar Pei dogs think A1a is the coolest!

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Asirpa inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Asirpa is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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