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Argos

Mixed Breed

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“Argos is a Kill Shelter Survivor. We adopted him when he was three months old. Argos has the best dog smile ever and has a great sense of humor. He is also a math genius for a dog. Argos loves people, dogs and cats…he’s very social. He is especially loves children, puppies and kittens. We used to get stopped by strangers quite a bit when we walked him because in his prime he looked exactly like Disney’s Tramp in Lady and the Tramp.”

Instagram tag
@Sweet_Kitty_Beans

Place of Birth

Mansfield, Ohio, USA

Current Location

Detroit, Michigan, USA

From

Toledo, OH, USA

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Genetic Breed Result

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Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Chow Chow

This distinctive-looking dog breed has a proud, independent spirit that some describe as catlike. Often aloof and suspicious of strangers, the Chow Chow may not be a cuddle buddy, but for the right person, they are a fiercely loyal companion.

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Cocker Spaniel

Cocker Spaniels are handsome and intelligent hunting dogs that are also well-suited to life as a loving family pet.

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Beagle

The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.

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Basset Hound

Basset Hounds are widely adored, short-legged and long-bodied hunting dogs that are considered great family companions.

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Boxer

Developed in Germany, the Boxer is a popular family dog: patient, loyal and smart-requiring lots of exercise and proper training. For active families or owners looking for a rambunctious jogging buddy, Boxers may be the perfect breed. Boxers delight their humans with their sense of humor and affectionate nature.

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German Shepherd Dog

German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.

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Dogs Like Argos

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Discover dogs who share a similar breed mix to Argos. A higher score means the two dogs have more of their breed mix in common. A score of 100% means they share the exact same breed mix!

Click or tap on a pic to learn more about each dog and see an in-depth comparison of their DNA, breeds, and more.

DNA Breed Origins

Breed colors:
Chow Chow
Cocker Spaniel
Beagle
Basset Hound
Boxer
German Shepherd Dog
Supermutt

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Argos
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Mixed Mixed Beagle mix Chow Chow / German Shepherd Dog mix Cocker Spaniel / Basset Hound mix Chow Chow / Boxer mix Beagle Mixed Chow Chow German Shepherd Dog mix Cocker Spaniel Basset Hound mix Chow Chow Boxer mix

Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Argos’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Argos is at increased risk for one genetic health condition.

And inherited two variants that you should learn more about.

Intervertebral Disc Disease (Type I)

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Argos inherited both copies of the variant we tested

How to interpret this result

Argos has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Dilated Cardiomyopathy, DCM1

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Argos inherited one copy of the variant we tested

What does this result mean?

Our research indicates that this genetic variant is not likely to increase the risk that Argos will develop this disease.

Scientific Basis

Dogs with similar breeds to Argos are not likely to have increased risk of developing the disease. Research has indicated increased risk in other breeds that are not found in Argos.

What is Dilated Cardiomyopathy, DCM1?

DCM is the most common acquired heart disease of adult dogs. The heart has two heavily muscled ventricles that pump blood away from the heart. This disease causes progressive weakening of the ventricles by reducing the muscle mass, which causes the ventricles to dilate. Dilated ventricles do not contract and circulate oxygenated blood well, which eventually leads to heart failure.

ALT Activity

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Argos inherited one copy of the variant we tested

Why is this important to your vet?

Argos has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Argos has this genotype, as ALT is often used as an indicator of liver health and Argos is likely to have a lower than average resting ALT activity. As such, an increase in Argos’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity

Identified in German Shepherd Dogs

Factor VII Deficiency

Identified in Beagles

Hemophilia A

Identified in Boxers

Hemophilia A

Identified in German Shepherd Dogs

Hemophilia A

Identified in German Shepherd Dogs

Thrombopathia

Identified in Basset Hounds

Canine Leukocyte Adhesion Deficiency Type III, CLAD III

Identified in German Shepherd Dogs

Pyruvate Kinase Deficiency

Identified in Beagles

Platelet Factor X Receptor Deficiency, Scott Syndrome

Identified in German Shepherd Dogs

X-linked Severe Combined Immunodeficiency, X-SCID

Identified in Basset Hounds

Progressive Retinal Atrophy, prcd

Identified in Cocker Spaniels

Progressive Retinal Atrophy, crd4/cord1

Identified in Beagles

Day Blindness

Identified in German Shepherd Dogs

Primary Open Angle Glaucoma

Identified in Beagles

Congenital Stationary Night Blindness

Identified in Beagles

Urate Kidney & Bladder Stones

Identified in German Shepherd Dogs

Familial Nephropathy

Identified in Cocker Spaniels

Anhidrotic Ectodermal Dysplasia

Identified in German Shepherd Dogs

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

Identified in German Shepherd Dogs

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII

Identified in German Shepherd Dogs

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

Identified in Cocker Spaniels

Neonatal Cerebellar Cortical Degeneration

Identified in Beagles

Degenerative Myelopathy, DM

Identified in Boxers and German Shepherd Dogs

Acral Mutilation Syndrome

Identified in Cocker Spaniels

Exercise-Induced Collapse, EIC

Identified in Cocker Spaniels

Hypocatalasia, Acatalasemia

Identified in Beagles

Cobalamin Malabsorption

Identified in Beagles

Musladin-Lueke Syndrome, MLS

Identified in Beagles

Osteogenesis Imperfecta

Identified in Beagles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Argos’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B92/93

Map

B1

Argos’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B92/93

Argos’s Haplotype

Part of the B1 haplogroup, the B92/93 haplotype occurs most commonly in Doberman Pinschers, West Highland White Terriers and American Pit Bull Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Through Argos’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.4

Map

A1a

Argos’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.4

Argos’s Haplotype

Part of the large A1a haplogroup, this haplotype occurs in village dogs in Colombia. It is common in small dogs like Dachshund, Miniature Dachshund, and Chihuahuas, but can also be found in larger breeds like Golden Retrievers.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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