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Annie

Mixed Breed

“Annie is a rescue, found at 6 wks old with her exhausted, overbred mom on a road in western NC, dumped off like trash. Annie is sweet and affectionate, kisses us and wags her tail a lot. She's alert and watchful, barks when she's thinks something isn't right. She gazes at her favorite people for long stretches. She can throw a blanket up into the air with her nose into just the right shape to snuggle under! We can read her emotions with her unique ears, which are expressive and very move-able!”

Place of Birth
Greenville, North Carolina, USA
Current Location
Ambler, Pennsylvania, USA
From
Almost Home Animal Shelter, Pennsauken Highway, Pennsauken Township, NJ, USA

This dog has been viewed 402 times and been given 14 wags

Genetic Breed Result

Learn how it’s done

Mixed Breed

50.0% Beagle
21.1% Rat Terrier
8.6% Siberian Husky
6.7% Bulldog
6.1% German Shepherd Dog
7.5% Supermutt

Embark Supermutt analysis

What’s in that Supermutt? There may be small amounts of DNA from these distant ancestors:

Beagle Beagle
The Beagle is a scent hound and a great family pet. They are known for being affectionate and having loud voices.
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Rat Terrier Rat Terrier
The Rat Terrier is an American dog breed with a background as a farm dog and hunting companion.
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Siberian Husky Siberian Husky
Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.
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Bulldog Bulldog
Originally a bull-baiting dog, bulldogs today are gentle and loving while still carrying the stocky frame of their forbearers.
Learn More
German Shepherd Dog German Shepherd Dog
German Shepherds are confident, courageous dogs with a keen sense of smell and notable intelligence. These are active working dogs who excel at many canine sports and tasks -- they are true utility dogs! Their versatility combined with their loyal companionship has them consistently listed as one of the most popular breeds in the United States.
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Genetic Stats


Wolfiness

0.3 % LOW Learn More

Predicted Adult Weight
Genetic Age
44 human years Learn More
Based on the date of birth provided

Breed Mix Matches

Explore other Embark dogs who have breed mixes that are similar to Annie’s.
A Mix Match of 100 means they are the exact same breed mix!

DNA Breed Origins

What’s this?
Breed colors:
Beagle
Rat Terrier
Siberian Husky
Bulldog
German Shepherd Dog
Supermutt

Would you like more information? Have you found a lost dog wearing an Embark dog tag? You can contact us at:

Explore by tapping the parents and grandparents.
 
Family Tree From Embark PARENTS GRANDPARENTS GREAT GRANDPARENTS Beagle Mixed Beagle Beagle Rat Terrier / Bulldog mix Siberian Husky / German Shepherd Dog mix Beagle Beagle Beagle Beagle Rat Terrier Bulldog mix Siberian Husky mix German Shepherd Dog mix

Our algorithms predict this is the most likely family tree to explain Annie’s breed mix, but this family tree may not be the only possible one.

Summary

0
AT RISK
0
CARRIER
172
CLEAR
Tap above or scroll down to see more

Clinical Traits

These clinical traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal

Annie has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Annie has this genotype, as ALT is often used as an indicator of liver health and Annie is likely to have a lower than average resting ALT activity. As such, an increase in Annie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

Genetic Health Conditions

A genetic health condition indicates a genetic mutation that increases the risk that an animal develops a specific disease.

Not At Risk

Good news! Annie did not test positive for any of the genetic conditions that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Annie’s diagnosis and treatment if she gets sick in the future.

Not A Carrier

Good news! Annie is not a carrier for any of the genetic conditions that Embark tests for.

Common Conditions

Good news! Annie tested clear for 24 genetic conditions that are common in her breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Annie.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Beagles, but not Annie.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Annie.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Annie.

Canine Leukocyte Adhesion Deficiency Type III, LAD3
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Annie.

Pyruvate Kinase Deficiency
(PKLR Exon 7 Beagle Variant)
Blood

This is a disease of red blood cells characterized by low energy level, jaundiced skin, and pale and cool extremities. Dogs affected with PKD have red blood cells that ha…

Seen in Beagles, but not Annie.

Progressive Retinal Atrophy - crd4/cord1
(RPGRIP1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

Seen in Beagles, but not Annie.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Annie.

Canine Multifocal Retinopathy
cmr1 (BEST1 Exon 2)
Eyes

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. CMR is typically only identified when a vet examines the eye which, in dogs with C…

Seen in Bulldogs, but not Annie.

Glaucoma
Primary Open Angle Glaucoma (ADAMTS10 Exon 17)
Eyes

A disease that affects humans and dogs alike; this is an adult-onset, medically manageable condition that causes high intraocular pressure (IOP). If left untreated, it ca…

Seen in Beagles, but not Annie.

Primary Lens Luxation
(ADAMTS17)
Eyes

This surgically correctable condition causes the lens to spontaneously detach from its normal residence within the pupil, leading to reduced visual acuity and irritation …

Seen in Rat Terriers, but not Annie.

Hyperuricosuria and Hyperuricemia or Urolithiasis, HUU
(SLC2A9)
Kidney and Bladder

This condition causes kidney and bladder stones composed of urate; if caught early, it is responsive to dietary management. Uric acid is an intermediate of purine metabol…

Seen in Bulldogs, German Shepherd Dogs, but not Annie.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Annie.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis, RCND
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Annie.

Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Annie.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Annie.

Cerebellar Abiotrophy, Neonatal Cerebellar Cortical Degeneration, NCCD
(SPTBN2)
Brain and Spinal Cord

Known as the “oldest” (even reptiles and more ancient species have them!) part of the brain, the cerebellum fine-tunes motor signals from the brain to the muscles, allowi…

Seen in Beagles, but not Annie.

Degenerative Myelopathy, DM
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in German Shepherd Dogs, but not Annie.

Fetal-Onset Neonatal Neuroaxonal Dystrophy
(MFN2)
Brain and Spinal Cord

This group of diseases center around the neuronal axon, a specialized cellular structure that helps our nervous systems relay information across great distances. Remember…

Seen in Beagles, but not Annie.

Hypocatalasia, Acatalasemia
(CAT)
Metabolic

This condition causes no ill effects in the majority of dogs; however, some dogs can suffer from mouth ulcers leading to difficulty eating and increased susceptibility to…

Seen in Beagles, but not Annie.

Imerslund-Grasbeck Syndrome, Selective Cobalamin Malabsorption
(CUBN Exon 8)
Gastrointestinal

This is a treatable gastrointestinal disease where dogs cannot absorb cobalamin, often causing them to be runty with poor energy levels. Cobalamin is required for synthes…

Seen in Beagles, but not Annie.

Musladin-Lueke Syndrome
(ADAMTSL2)
Skin & Connective Tissues

First characterized in the Beagle, this condition causes abnormally strong connections between the structural proteins that provide strength and integrity to tissues like…

Seen in Beagles, but not Annie.

Osteogenesis Imperfecta, Brittle Bone Disease
(COL1A2)
Skeletal

A disease of bone strength and flexibilty, affected dogs often present to the vet for spontaneous bone fractures, tooth fractures and loss, and joint pain; these symptoms…

Seen in Beagles, but not Annie.

Chondrodystrophy and Intervertebral Disc Disease, CDDY/IVDD, Type I IVDD
(FGF4 retrogene - CFA12)
Skeletal

Chondrodystrophy (CDDY) refers to the "long and low" body shape characteristic of many dog breeds including Dachshunds and Corgis. Recently, a mutation was discovered tha…

Seen in Beagles, but not Annie.

Other Conditions:
Clear of 148

Annie is clear of 148 other genetic conditions that Embark tests for.
Explore the genetics behind your dog’s appearance, size, and genetic diversity.
Base Coat Color

Base Coat Color

Dark or Light Fur
E (Extension) Locus
Can have dark fur
Brown or Black Pigment
B (Brown) Locus
Black or gray fur and skin
Color Dilution
D (Dilute) Locus
Dark (non-dilute) fur and skin
Coat Color Modifiers

Coat Color Modifiers

Hidden Patterning
K (Dominant Black) Locus
More likely to have a mostly solid black or brown fur coat
Body Pattern
A (Agouti) Locus
No impact on coat pattern
Facial Fur Pattern
E (Extension) Locus
Can have black masking (dark facial fur)
Saddle Tan
No impact on coat pattern
Merle
M (Merle) Locus
Unlikely to have merle pattern
Other Coat Traits

Other Coat Traits

Furnishings LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows)
Coat Length
Likely short or mid-length coat
Shedding
Likely heavy/seasonal shedding
Coat Texture
Likely straight coat
Hairlessness (Xolo type) LINKAGE
Very unlikely to be hairless
Hairlessness (Terrier type)
Very unlikely to be hairless
Oculocutaneous Albinism Type 2 LINKAGE
Likely not albino
Other Body Features

Other Body Features

Muzzle Length
Likely medium or long muzzle
Tail Length
Likely normal-length tail
Hind Dew Claws
Unlikely to have hind dew claws
Back Muscling & Bulk (Large Breed)
Likely normal muscling
Eye Color LINKAGE
Less likely to have blue eyes
Body Size

Body Size

Body Size 1
Intermediate
Body Size 2
Larger
Body Size 3
Larger
Body Size 4
Smaller
Body Size 5
Larger
Performance

Performance

Altitude Adaptation
Normal altitude tolerance

Through Annie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A2a

Map

A1e

Annie’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A2a

Annie’s Haplotype

Part of the large A1e haplogroup, we see this haplotype in village dogs up and down the Americas as well as French Polynesia. Among the breed dogs we have detected it in, we see it most frequently in English Springer Spaniels, Papillons, and Collies.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Annie inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Annie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.