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“Enzo”
Angel’s Creek Lorenzo

Pomsky

No bio has been provided yet

Instagram tag
@angelscreekpomskies

Place of Birth

Lancaster, Ohio, USA

Current Location

Bradley, Illinois, USA

From

Lancaster, Ohio, USA

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Registration

International Pomsky Association (IPA): F11832
Microchip: 90011188045772

Genetic Breed Result

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Siberian Husky

Bred initially in Northern Siberia, the Siberian Husky is a medium-sized working dog who is quick and light on their feet. Their moderately compact and well furred body, erect ears and brush tail suggest their Northern heritage. Huskies are very active and energetic and are known for being long distance sled dogs.

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Pomeranian

The Pomeranian is a cocky, animated companion with an extroverted personality.

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DNA Breed Origins

Breed colors:
Siberian Husky
Pomeranian

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Health Summary

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Enzo has one variant that you should let your vet know about.

ALT Activity

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Enzo inherited one copy of the variant we tested

Why is this important to your vet?

Enzo has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Enzo has this genotype, as ALT is often used as an indicator of liver health and Enzo is likely to have a lower than average resting ALT activity. As such, an increase in Enzo’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, rcd3 (PDE6A)

Identified in Pomeranians

X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)

Identified in Siberian Huskies

Urate Kidney & Bladder Stones (SLC2A9)

Identified in Pomeranians

GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)

Identified in Siberian Huskies

Degenerative Myelopathy, DM (SOD1A)

Identified in Siberian Huskies

Oculocutaneous Albinism, OCA (SLC45A2, Small Breed Variant)

Identified in Pomeranians

Hereditary Vitamin D-Resistant Rickets (VDR)

Identified in Pomeranians

Additional Genetic Conditions

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Through Enzo’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A247

Map

A1d

Angel’s Creek Lorenzo’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A247

Angel’s Creek Lorenzo’s Haplotype

Part of the large A1d haplogroup, this common haplotype occurs in village dogs all over the world. Among the 32 breeds we have sampled it in, the most common occurrences include Boxers, Labrador Retrievers, and Papillons.

The vast majority of Rottweilers have the A1d haplogroup.

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Through Enzo’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A

Haplotype

Hc.1

Map

A

Angel’s Creek Lorenzo’s Haplogroup

A is the distant relative of some of the most numerous paternal lineages in the world. Characterized by a single sub-lineage, this is a rare and interesting paternal line! The A line is found most commonly in Siberian Huskies and in Alaskan village dogs. It seems plausible that this paternal lineage diverged within the last 10,000 years from a group arriving with the first Arctic explorers. The recent ancestors of dogs with this lineage actually allowed humans to survive in some of the most forbidding conditions on the face of the earth!

Hc.1

Angel’s Creek Lorenzo’s Haplotype

The lone member of the A haplogroup, this haplotype occurs most commonly in Siberian Huskies and village dogs from Alaska.

Siberian Huskys are the only breed to have the A haplogroup.

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