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Amillionaire

American Bully

“Amillionaire is from BurrNation K9’s. Her parents are Grennan’s Magneto and XDP’s Azul Ice. Amilli spends most of her time working out on the spring pole and basking in the sun.”

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Registration

United Kennel Club (UKC):

Genetic Breed Result

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American Bully

The American Bully may look intimidating with its muscular build, but these dogs are bred to be the ideal family or companion dog. This breed is notable for coming in several different size and type varieties, so there's a lot of diversity in their appearance. They're a newer breed, originating in the 80s and 90s in the United States.

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Here’s what Amillionaire’s family tree may have looked like.
While there may be other possible configurations of her family’s relationships, this is the most likely family tree to explain Amillionaire’s breed mix.

Breed Reveal Video

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Health Summary

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Amillionaire inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Progressive Retinal Atrophy, crd4/cord1

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Amillionaire inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Amillionaire’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Amillionaire is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Progressive Retinal Atrophy, crd4/cord1?

PRA-CRD4/cord1 is a retinal disease that causes progressive, non-painful vision loss over a 1-2 year period. The retina contains cells, called photoreceptors, that collect information about light and send signals to the brain. There are two types of photoreceptors: rods, for night vision and movement, and cones, for day vision and color. This type of PRA leads to early loss of cone cells, causing day blindness before night blindness.

Degenerative Myelopathy, DM

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Amillionaire inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Amillionaire’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Amillionaire is unlikely to develop this condition due to this variant because she only has one copy of the variant.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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Amillionaire inherited one copy of the variant we tested

Why is this important to your vet?

Amillionaire has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Amillionaire has this genotype, as ALT is often used as an indicator of liver health and Amillionaire is likely to have a lower than average resting ALT activity. As such, an increase in Amillionaire’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Progressive Retinal Atrophy, crd1

Identified in American Bullies

Canine Multifocal Retinopathy, cmr1

Identified in American Bullies

Urate Kidney & Bladder Stones

Identified in American Bullies

Neuronal Ceroid Lipofuscinosis, Cerebellar Ataxia, NCL4A

Identified in American Bullies

Neuronal Ceroid Lipofuscinosis 10, NCL 10

Identified in American Bullies

L-2-Hydroxyglutaricaciduria, L2HGA

Identified in American Bullies

Ichthyosis

Identified in American Bullies

Additional Genetic Conditions

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Traits

Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Amillionaire’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1d

Haplotype

A248

Map

A1d

Amillionaire’s Haplogroup

This female lineage can be traced back about 15,000 years to some of the original Central Asian wolves that were domesticated into modern dogs. The early females that represent this lineage were likely taken into Eurasia, where they spread rapidly. As a result, many modern breed and village dogs from the Americas, Africa, through Asia and down into Oceania belong to this group! This widespread lineage is not limited to a select few breeds, but the majority of Rottweilers, Afghan Hounds and Wirehaired Pointing Griffons belong to it. It is also the most common female lineage among Papillons, Samoyeds and Jack Russell Terriers. Considering its occurrence in breeds as diverse as Afghan Hounds and Samoyeds, some of this is likely ancient variation. But because of its presence in many modern European breeds, much of its diversity likely can be attributed to much more recent breeding.

A248

Amillionaire’s Haplotype

Part of the large A1d haplogroup, this haplotype has been detected in village dogs in French Polynesia and Colombia. Among breeds, it occurs in Jack Russell Terriers, Fox Terrier Wires, and Cocker Spaniels.

The vast majority of Rottweilers have the A1d haplogroup.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Amillionaire inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Amillionaire is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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