Akela inherited one copy of the variant we tested
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Changes to this dog’s profile
- On 1/8/2019 changed name from "Akela " to "Akela"
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Health Summary
Akela has one variant that you should let your vet know about.
ALT Activity
Why is this important to your vet?
Akela has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Akela has this genotype, as ALT is often used as an indicator of liver health and Akela is likely to have a lower than average resting ALT activity. As such, an increase in Akela’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.
What is ALT Activity?
Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.
Breed-Relevant Genetic Conditions
Multiple Drug Sensitivity (ABCB1)
Identified in German Shepherd Dogs
Variant not detected
Factor VII Deficiency (F7 Exon 5)
Identified in Alaskan Malamutes
Variant not detected
Hemophilia A (F8 Exon 11, German Shepherd Variant 1)
Identified in German Shepherd Dogs
Variant not detected
Hemophilia A (F8 Exon 1, German Shepherd Variant 2)
Identified in German Shepherd Dogs
Variant not detected
Canine Leukocyte Adhesion Deficiency Type III, CLAD III (FERMT3, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected
Progressive Retinal Atrophy, prcd (PRCD Exon 1)
Identified in Norwegian Elkhounds
Variant not detected
X-Linked Progressive Retinal Atrophy 1, XL-PRA1 (RPGR)
Identified in Siberian Huskies
Variant not detected
Day Blindness (CNGA3 Exon 7, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected
Primary Open Angle Glaucoma (ADAMTS10 Exon 9, Norwegian Elkhound Variant)
Identified in Norwegian Elkhounds
Variant not detected
Urate Kidney & Bladder Stones (SLC2A9)
Identified in German Shepherd Dogs
Variant not detected
Anhidrotic Ectodermal Dysplasia (EDA Intron 8)
Identified in German Shepherd Dogs
Variant not detected
Renal Cystadenocarcinoma and Nodular Dermatofibrosis (FLCN Exon 7)
Identified in German Shepherd Dogs
Variant not detected
Mucopolysaccharidosis Type VII, Sly Syndrome, MPS VII (GUSB Exon 3, German Shepherd Variant)
Identified in German Shepherd Dogs
Variant not detected
GM1 Gangliosidosis (GLB1 Exon 15, Alaskan Husky Variant)
Identified in Siberian Huskies
Variant not detected
Degenerative Myelopathy, DM (SOD1A)
Identified in German Shepherd Dogs and Siberian Huskies
Variant not detected
Alaskan Malamute Polyneuropathy, AMPN (NDRG1 SNP)
Identified in Alaskan Malamutes
Variant not detected
Chondrodystrophy (ITGA10, Norwegian Elkhound and Karelian Bear Dog Variant)
Identified in Norwegian Elkhounds
Variant not detected