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“Aggie”
Agatha Chocolay Superior Freberg

Mixed Ancestry

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“She loves to play. She is everyone's friend. A super sweet loyal gal. Everyone thinks she is so beautiful.”

Place of Birth

Allendale, MI, USA

Current Location

Skandia, Michigan, USA

From

Allendale, MI, USA

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Genetic Breed Result

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Genetic Stats

Predicted Adult Weight

51 lbs

Genetic Age
32 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Border Collie
Poodle (Standard)

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Changes to this dog’s profile
  • On 11/21/2020 changed name from "Agatha" to "Agatha Chocolay Superior Freberg"

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Health Summary

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Aggie has one variant that you should let your vet know about.

ALT Activity

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Aggie inherited one copy of the variant we tested

Why is this important to your vet?

Aggie has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Aggie has this genotype, as ALT is often used as an indicator of liver health and Aggie is likely to have a lower than average resting ALT activity. As such, an increase in Aggie’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Border Collies

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Border Collies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles

Collie Eye Anomaly (NHEJ1)

Identified in Border Collies

Goniodysgenesis and Glaucoma, Pectinate Ligament Dysplasia, PLD (OLFM3)

Identified in Border Collies

Primary Lens Luxation (ADAMTS17)

Identified in Border Collies

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Border Collies

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)

Identified in Border Collies

Cobalamin Malabsorption (CUBN Exon 53, Border Collie Variant)

Identified in Border Collies

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Aggie’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A226

Map

A1e

Agatha Chocolay Superior Freberg’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A226

Agatha Chocolay Superior Freberg’s Haplotype

Part of the large A1e haplogroup, we have spotted this haplotype in village dogs in Central and South America and Papua New Guinea. Among the 10 breeds we have detected it in, we see it most frequently in Border Collies, Doberman Pinschers, and Samoyeds.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Aggie inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Aggie is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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