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AK 3 Norabak Village

Armenian Gampr

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“11 year old female. Will be bred to Red male packmate this winter. Natural Bobtail I am assuming”

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Registration

Armenian Gampr Club of America (AGCA):

Genetic Breed Result

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Armenian Gampr

The Armenian Gampr is an ancient, working livestock guardian dog originally bred in the southern Caucasus Mountains. The Gampr is considered a landrace rather than a breed with a closed population; they are genetically diverse with an emphasis on function rather than form. There are several regional variants of the Gampr.

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Genetic Stats

Wolfiness

1.8 % HIGH

Predicted Adult Weight

89 lbs

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Changes to this dog’s profile
  • On 8/23/2018 changed name from "AG 3 Vartenis" to "AK 3 Vartenis"
  • On 8/23/2018 changed name from "AK 3 Vartenis" to "AK 3 Norabak Village"

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Our algorithms predict this is the most likely family tree to explain AK 3 Norabak Village’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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AK 3 Norabak Village inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

GM2 Gangliosidosis

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AK 3 Norabak Village inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), AK 3 Norabak Village is unlikely to develop this condition due to the variant. This result may be important if you decide to breed this dog - we recommend genetic testing potential mates for this condition.

What is GM2 Gangliosidosis?

A lysosome is a structure within the cell that digests and removes waste. When the lysosome cannot recycle waste properly, the waste accumulates and causes the cell to die. This form of lysosomal storage disease (gangliosidosis) is caused by buildup of a fatty substance known as ganglioside, especially in cells of the nervous system.

Degenerative Myelopathy, DM

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AK 3 Norabak Village inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), AK 3 Norabak Village is unlikely to develop this condition due to the variant. This result may be important if you decide to breed this dog - we recommend genetic testing potential mates for this condition.

What is Degenerative Myelopathy, DM?

The dog equivalent of Amyotrophic Lateral Sclerosis, or Lou Gehrig’s disease, DM is a progressive degenerative disorder of the spinal cord. Because the nerves that control the hind limbs are the first to degenerate, the most common clinical signs are back muscle wasting and gait abnormalities.

ALT Activity

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AK 3 Norabak Village inherited one copy of the variant we tested

Why is this important to your vet?

AK 3 Norabak Village has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that AK 3 Norabak Village has this genotype, as ALT is often used as an indicator of liver health and AK 3 Norabak Village is likely to have a lower than average resting ALT activity. As such, an increase in AK 3 Norabak Village’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through AK 3 Norabak Village’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A295

Map

A1e

AK 3 Norabak Village’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A295

AK 3 Norabak Village’s Haplotype

Part of the large A1e haplogroup, we have found this haplotype in village dogs in Afghanistan, Liberia, and Qatar. We see this haplotype most frequently in Scottish Terriers, Jack Russell Terriers, and Brussels Griffons.

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that AK 3 Norabak Village inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since AK 3 Norabak Village is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

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