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“Fig”
ADAMS RANCH FIG

Australian Cattle Dog

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Place of Birth

Pinon Hills, CA, USA

Current Location

Los Angeles, California, USA

From

Pinon Hills, CA, USA

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Registration

American Kennel Club (AKC): DN64827002
Microchip: 956 000 012 615 198

Genetic Breed Result

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Australian Cattle Dog

A classic cattle dog, Australian Cattle Dogs were developed from a mixture of breeds in Australia in the 19th century, and still maintain their energetic herding instincts today.

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Changes to this dog’s profile
  • On 1/29/2021 changed name from "ADAMS RANCH MAXWELL" to "ADAMS RANCH FIG"
  • On 1/28/2021 changed name from "ADAMS RANCH Maxwell" to "ADAMS RANCH MAXWELL"
  • On 1/28/2021 changed name from "ADAMS RANCH DN6482701" to "ADAMS RANCH Maxwell"

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Health Summary

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Fig inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency

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Fig inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Fig is unlikely to develop this condition due to the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency?

Affecting an enzyme required for red blood cell and skeletal muscle cell energy production, phosphofructokinase (PFK) deficiency causes red blood cells and skeletal muscle rupture and injury during strenuous exercise, overheating, or prolonged barking or panting.

ALT Activity

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Fig inherited one copy of the variant we tested

Why is this important to your vet?

Fig has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Fig has this genotype, as ALT is often used as an indicator of liver health and Fig is likely to have a lower than average resting ALT activity. As such, an increase in Fig’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Australian Cattle Dogs

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Australian Cattle Dogs

Collie Eye Anomaly (NHEJ1)

Identified in Australian Cattle Dogs

Primary Lens Luxation (ADAMTS17)

Identified in Australian Cattle Dogs

Cystinuria Type II-A (SLC3A1, Australian Cattle Dog Variant)

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Australian Cattle Dogs

Neuronal Ceroid Lipofuscinosis 8, NCL 8 (CLN8, Australian Shepherd Variant)

Identified in Australian Cattle Dogs

Late-Onset Neuronal Ceroid Lipofuscinosis, NCL 12 (ATP13A2, Australian Cattle Dog Variant)

Identified in Australian Cattle Dogs

Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)

Identified in Australian Cattle Dogs

Additional Genetic Conditions

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Coat Color

Coat Color

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Other Coat Traits

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Body Size

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Performance

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Through Fig’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1e

Haplotype

A428

Map

A1e

ADAMS RANCH FIG’s Haplogroup

This female lineage likely stems from some of the original Central Asian wolves that were domesticated into modern dogs starting about 15,000 years ago. It seemed to be a fairly rare dog line for most of dog history until the past 300 years, when the lineage seemed to “explode” out and spread quickly. What really separates this group from the pack is its presence in Alaskan village dogs and Samoyeds. It is possible that this was an indigenous lineage brought to the Americas from Siberia when people were first starting to make that trip themselves! We see this lineage pop up in overwhelming numbers of Irish Wolfhounds, and it also occurs frequently in popular large breeds like Bernese Mountain Dogs, Saint Bernards and Great Danes. Shetland Sheepdogs are also common members of this maternal line, and we see it a lot in Boxers, too. Though it may be all mixed up with European dogs thanks to recent breeding events, its origins in the Americas makes it a very exciting lineage for sure!

A428

ADAMS RANCH FIG’s Haplotype

Part of the A1e haplogroup, the A428 haplotype occurs most commonly in American Village Dogs. It's a rare find!

Some other Embark dogs with this haplotype:

Irish Wolfhounds are a consistent carrier of A1e.

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Through Fig’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.53

Map

A1a

ADAMS RANCH FIG’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.53

ADAMS RANCH FIG’s Haplotype

Part of the A1a haplogroup, this haplotype occurs most frequently in Golden Retrievers, Border Collies, and the Coton de Tulear.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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