Venn diagram

Compare your dogs to Addy Select one to begin:

“Addy”
Adalyn Kiss of Caramel

English Cocker Spaniel

“Always smiling, hugs you and sleeps on you 😊she’s the sweetest dog you ever seen”

Place of Birth

Bowling Green, Kentucky, USA

Current Location

Bowling Green, Kentucky, USA

This dog has been viewed and been given 3 wags

Registration

American Kennel Club (AKC): SS27866107

Genetic Breed Result

Loading...

English Cocker Spaniel

English Cockers are a medium-size dog with long ears and a happy disposition. The name Cocker comes from their use to hunt woodcock in England, although English Cockers have been used to hunt many other types of birds as well. They make great companion dogs for people who can give them the exercise they need.

Learn More

Loading...

Start a conversation! Message this dog’s owner.

Loading...

Explore

Health Summary

danger icon

Addy is at increased risk for one genetic health condition.

And inherited one variant that you should learn more about.

Intervertebral Disc Disease (Type I)

danger icon

Addy inherited both copies of the variant we tested

How to interpret this result

Addy has two copies of an FGF4 retrogene on chromosome 12. In some breeds such as Beagles, Cocker Spaniels, and Dachshunds (among others) this variant is found in nearly all dogs. While those breeds are known to have an elevated risk of IVDD, many dogs in those breeds never develop IVDD. For mixed breed dogs and purebreds of other breeds where this variant is not as common, risk for Type I IVDD is greater for individuals with this variant than for similar dogs.

What is Intervertebral Disc Disease (Type I)?

Type I Intervertebral Disc Disease (IVDD) is a back/spine issue that refers to a health condition affecting the discs that act as cushions between vertebrae. With Type I IVDD, affected dogs can have a disc event where it ruptures or herniates towards the spinal cord. This pressure on the spinal cord causes neurologic signs which can range from a wobbly gait to impairment of movement. Chondrodystrophy (CDDY) refers to the relative proportion between a dog’s legs and body, wherein the legs are shorter and the body longer. There are multiple different variants that can cause a markedly chondrodystrophic appearance as observed in Dachshunds and Corgis. However, this particular variant is the only one known to also increase the risk for IVDD.

Familial Nephropathy

warn icon

Addy inherited one copy of the variant we tested

What does this result mean?

This variant should not impact Addy’s health. This variant is inherited in an autosomal recessive manner, meaning that a dog needs two copies of the variant to show signs of this condition. Addy is unlikely to develop this condition due to this variant because she only has one copy of the variant.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of her offspring. You can email breeders@embarkvet.com to discuss with a genetic counselor how the genotype results should be applied to a breeding program.

What is Familial Nephropathy?

Protein Losing Nephropathy causes inappropriate loss of protein in the urine. Certain parts of the kidney act as a sieve where ions, small molecules like urea, and water are filtered out of the blood into the urine. In PLN, the sieve is compromised and protein moves in the urine. This leads to muscle wasting, abnormal fluid accumulation in the skin and limbs, and kidney failure.

Breed-Relevant Genetic Conditions

good icon

Bernard-Soulier Syndrome, BSS (GP9, Cocker Spaniel Variant)

Identified in English Cocker Spaniels

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in English Cocker Spaniels

Glycogen storage disease Type VII, Phosphofructokinase Deficiency, PFK Deficiency (PFKM, Whippet and English Springer Spaniel Variant)

Identified in English Cocker Spaniels

Acral Mutilation Syndrome (GDNF-AS, Spaniel and Pointer Variant)

Identified in English Cocker Spaniels

Exercise-Induced Collapse, EIC (DNM1)

Identified in English Cocker Spaniels

Additional Genetic Conditions

good icon

Explore

Traits

Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

Loading...

Explore

Through Addy’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B74

Map

B1

Adalyn Kiss of Caramel’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B74

Adalyn Kiss of Caramel’s Haplotype

Part of the large B1 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

Loading...

Explore

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Addy inherited from her mom and dad? Check out her breed breakdown.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Addy is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.

Loading...

Explore