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Achilles

Miniature Pinscher

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“Achilles both looks and acts weird as hell, and how he turned out to be a purebred animal is beyond me, but I’m proud of him. I was convinced my best friend was an alien, but it turns out he is just a normal min pin!”

Current Location

Boise, Idaho, USA

From

Boise, ID, USA

This dog has been viewed and been given 38 wags

Genetic Breed Result

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Miniature Pinscher

The Miniature Pinscher is a small breed of dog originating from Germany. The breed's earliest ancestors may have included the German Pinscher mixed with Italian greyhounds and dachshunds.

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Breed Reveal Video

Our algorithms predict this is the most likely family tree to explain Achilles’s breed mix, but this family tree may not be the only possible one.

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Health Summary

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Achilles inherited two variants that you should learn more about.

And one variant that you should tell your vet about.

Canine Multifocal Retinopathy, cmr1

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Achilles inherited one copy of the variant we tested

What does this result mean?

Because this variant is inherited in an autosomal recessive manner (meaning dogs need two copies of the variant to develop the disease), Achilles is unlikely to develop this condition due to the variant.

What is Canine Multifocal Retinopathy, cmr1?

This is a non-progressive retinal disease that, in rare cases, can lead to vision loss. Dogs with larger lesions can suffer from vision loss. CMR is fairly non-progressive; new lesions will typically stop forming by the time a dog is an adult, and some lesions will even regress with time.

Hereditary Cataracts

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Achilles inherited one copy of the variant we tested

What does this result mean?

We do not know whether this increases the risk that Achilles will develop this disease.

Scientific Basis

Research studies for this variant have been based on dogs of other breeds. Not enough dogs with the breeds in Achilles have been studied to know whether or not this variant will increase Achilles’s risk of developing this disease.

What is Hereditary Cataracts?

Cataracts are the result of a progressive disease of the lens. The lens is normally a transparent structure of precisely organized fibers that lives in the pupil and focuses light. Cataracts cause the lens fibers to become disordered and turns the lens into a milky blue color. The lens is no longer transparent, light fails to reach the retina, and blindness is the end result. With this genetic mutation, dogs can develop cataracts at only a few weeks to months of age.

ALT Activity

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Achilles inherited one copy of the variant we tested

Why is this important to your vet?

Achilles has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Achilles has this genotype, as ALT is often used as an indicator of liver health and Achilles is likely to have a lower than average resting ALT activity. As such, an increase in Achilles’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Cystinuria Type II-B

Identified in Miniature Pinschers

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Base Coat Color

Base Coat Color

Coat Color Modifiers

Coat Color Modifiers

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through Achilles’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A4

Haplotype

A452

Map

A4

Achilles’s Haplogroup

The A4 maternal lineage is fairly rare. It is found in Cocker Spaniels, but A4 is also represented well among East Asian breeds including the Chinese Crested Dog, Shar-Pei and Shih Tzu. Moving away from Asia, it is also found among Chihuahuas (a very old breed!) and village dogs in Peru. This may be a lineage that moved into Western breeds because of their owners' tendencies to mix them up with Eastern breeds in the early modern period.

A452

Achilles’s Haplotype

Part of the A4 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

The popular Chihuahua breed descends from the A4 maternal line.

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Through Achilles’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.44

Map

A1b

Achilles’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.44

Achilles’s Haplotype

Part of the A1b haplogroup, this haplotype occurs primarily in Poodles and Belgian Sheepdogs.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

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