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Thor

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“Thor is so sweet and loves attention. Loves to get out and meet new people.”

This dog has been viewed 460 times and been given 2 wags

Genetic Breed Result

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58.9% Gray Wolf
16.7% German Shepherd Dog
14.3% Alaskan Malamute
5.1% Siberian Husky
5.0% Norwegian Elkhound
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Genetic Stats

Wolfiness: 34.2 % HIGH Learn More
Predicted Adult Weight: 64 lbs Learn More
Genetic Age: 30 human years Learn More

DNA Breed Origins

What’s this?
Breed colors:
Gray Wolf
German Shepherd Dog
Alaskan Malamute
Siberian Husky
Norwegian Elkhound

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Health

Traits

Maternal Haplotype

Paternal Haplotype

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Summary

0
AT RISK
0
CARRIER
164
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
Thor has two normal alleles at ALT.

Not At Risk

Good news! Thor did not test positive for any of the genetic diseases that Embark screens for. Read on to learn more about the conditions we test for, but rest assured that Thor does not have the mutations known to cause them.

It is still important to let your veterinarian know these results because they could help guide Thor’s diagnosis and treatment if he gets sick in the future. Many other diseases caused by environmental factors or undiscovered genetic variants can cause symptoms similar to diseases we test for. By ruling out these mutations, your veterinarian will be able to find the true cause more quickly. Your veterinarian will also know they can safely prescribe medications some dogs are sensitive to.

Not A Carrier

Good news! Thor is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Thor tested clear for 15 genetic conditions that are common in his breed mix.
Condition List

MDR1 Drug Sensitivity
(MDR1)
Clinical

Sensitivity to certain classes of drugs, notably the parasiticide ivermectin, as well as certain gastroprotectant and anti-cancer medications, occurs in dogs with mutatio…

Seen in German Shepherd Dogs, but not Thor.

Factor VII Deficiency
(F7 Exon 5)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in Alaskan Malamutes, but not Thor.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 11, Shepherd Variant 1)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Thor.

Factor VIII Deficiency, Hemophilia A
(F8 Exon 1, Shepherd Variant 2)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Seen in German Shepherd Dogs, but not Thor.

Canine Leukocyte Adhesion Deficiency Type III (LAD3)
(FERMT3)
Blood

A rare disorder of white blood cells, this causes increased susceptibility to infections and bleeding tendencies. Affected dogs present with a history of persistent skin …

Seen in German Shepherd Dogs, but not Thor.

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, nonpainful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are th…

Seen in Norwegian Elkhounds, but not Thor.

Achromatopsia
(CNGA3 Exon 7 German Shepherd Variant)
Eyes

This is a progressive, nonpainful disorder of the retina that affects color vision and light perception. Cone cells not only register color, they allow the dog to adjust …

Seen in German Shepherd Dogs, but not Thor.

Glaucoma
Primary Open Angle Glaucoma (ADAMTS10 Exon 9)
Eyes

A disease that affects humans and dogs alike, this is an adult onset, medically manageable condition that causes high intraocular pressure (IOP). Left untreated, it can l…

Seen in Norwegian Elkhounds, but not Thor.

X-linked Ectodermal Dysplasia, Anhidrotic Ectodermal Dysplasia
(EDA Intron 8)
Multisystem

This developmental condition can cause a scanty haircoat, malformed teeth, and few or absent sweat glands. Because dogs only have sweat glands on their paw pads, they are…

Seen in German Shepherd Dogs, but not Thor.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis (RCND)
(FLCN Exon 7)
Multisystem

A multiorgan syndrome best described in the German Shepherd Dog, affected dogs display thick skin nodules and signs of kidney disease, and should be evaluated by a veteri…

Seen in German Shepherd Dogs, but not Thor.

Mucopolysaccharidosis Type VII, Sly Syndrome
(GUSB Exon 3)
Multisystem

A type of lysosomal storage disease, this can cause skeletal abnormalities, growth retardation, and gait abnormalities, and can require close monitoring and special measu…

Seen in German Shepherd Dogs, but not Thor.

GM1 Gangliosidosis
(GLB1 Exon 15 Alaskan Husky Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Seen in Siberian Huskys, but not Thor.

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Seen in Gray Wolfs, German Shepherd Dogs, Alaskan Malamutes, Siberian Huskys, Norwegian Elkhounds, but not Thor.

Polyneuropathy, NDRG1 Malamute Variant
(NDRG1 Exon 4)
Brain and Spinal Cord

Polyneuropathy is a progressive neurologic disease that causes peripheral nerve dysfution. Peripheral nerves relay messages between the brain and spinal cord to the rest …

Seen in Alaskan Malamutes, but not Thor.

Malignant Hyperthermia
(RYR1)
Metabolic

This condition only manifests if affected dogs are treated with certain inhalant anesthetics, and can cause uncontrollable muscle contractions and a dangerous increase in…

Seen in Gray Wolfs, German Shepherd Dogs, Alaskan Malamutes, Siberian Huskys, Norwegian Elkhounds, but not Thor.

Other Conditions: Clear of 149

Thor is clear of 149 other genetic diseases that Embark tests for.

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Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
EE
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
ata
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red)
BB

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
II
Long Haircoat (FGF5)
GG
Shedding (MC5R)
CC
Curly Coat (KRT71)
CC
Hairlessness (FOXI3)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GA
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Health

Maternal Haplotype

Paternal Haplotype

Through Thor’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

A17

Map

A1a

Thor’s Haplogroup

A1a is the most common maternal lineage among Western dogs. This lineage traveled from the site of dog domestication in Central Asia to Europe along with an early dog expansion perhaps 10,000 years ago. It hung around in European village dogs for many millennia. Then, about 300 years ago, some of the prized females in the line were chosen as the founding dogs for several dog breeds. That set in motion a huge expansion of this lineage. It's now the maternal lineage of the overwhelming majority of Mastiffs, Labrador Retrievers and Gordon Setters. About half of Boxers and less than half of Shar-Pei dogs descend from the A1a line. It is also common across the world among village dogs, a legacy of European colonialism.

A17

Thor’s Haplotype

Part of the large A1a haplogroup, this common haplotype is found in village dogs across the globe. Among breed dogs, we find it most frequently in Labrador Retrievers, Boxers, and Mastiffs.

Some other Embark dogs with this haplotype:

Shar Pei dogs think A1a is the coolest!

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Health

Traits

Paternal Haplotype

Through Thor’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

Achille's Haplogroup

Haplotype

Achilles

Map

Achille's Haplogroup

Thor’s Haplogroup

This is a lineage that is unknown in dogs and may only be found in wolves. It is very different from all known dog lineages indicating a long time between the most recent common ancestor of canids in this lineage and domestic dogs.

Achilles

Thor’s Haplotype

This haplotype has been spotted in wolves and dogs with wolf ancestry. Not only is that pretty neat, but it also helps move science forward.

Some other Embark dogs with this haplotype:

The mysterious wolf hides many genetic mysteries unknown to science - like where this male lineage came from.

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Health

Traits

Maternal Haplotype