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Sunny Lion's In The Nyck of Thyme at A & A

“Nikki”
UKC CH Sunny Lion's In The Nyck of Thyme at A & A

Chihuahua

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Registration

AKC: TS43797101
Microchip: 933061600508150

Genetic Breed Result

Learn how it’s done

Chihuahua

Chihuahua Chihuahua
Chihuahuas have a huge personality that defies their tiny frame, known to be highly active and intelligent canines.
Learn More
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Genetic Stats


Predicted Adult Weight
Genetic Age
32 human years Learn More
Based on the date of birth provided

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Health Summary

Nikki inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Von Willebrand Disease Type II, Type II vWD

Nikki inherited one copy of the variant we tested

What does this result mean?

This result should not impact Nikki’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

This result should be taken into account as part of your breeding program. Nikki will pass this variant to ~50% of her offspring.

What is Von Willebrand Disease Type II, Type II vWD?

Von Willebrand Disease (vWD) is a type of coagulopathy, a disorder of blood clotting. There are multiple types of vWD, some common and some rare, with marked differences in severity. Please inform your veterinarian of your dog’s vWD status.


ALT Activity

Nikki inherited one copy of the variant we tested

Why is this important to your vet?

Nikki has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that Nikki has this genotype, as ALT is often used as an indicator of liver health and Nikki is likely to have a lower than average resting ALT activity. As such, an increase in Nikki’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Chihuahuas

Progressive Retinal Atrophy - crd4/cord1 (RPGRIP1)

Identified in Chihuahuas

Neuronal Ceroid Lipofuscinosis (MFSD8)

Identified in Chihuahuas

Spinocerebellar Ataxia with Myokymia and/or Seizures (KCNJ10)

Identified in Chihuahuas

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Chihuahuas

Additional Genetic Conditions

Explore the genetics behind your dog’s appearance and size.
Coat Color

Coat Color

E Locus (MC1R)
No dark mask or grizzle (Ee)
K Locus (CBD103)
More likely to have a patterned haircoat (kyky)
Intensity Loci LINKAGE
Any light hair likely white or cream (Dilute Red Pigmentation)
A Locus (ASIP)
Fawn Sable coat color pattern (ayay)
D Locus (MLPH)
Dark areas of hair and skin are not lightened (Dd)
B Locus (TYRP1)
Black or gray hair and skin (BB)
S Locus (MITF)
Likely solid colored, but may have small amounts of white (Ssp)
H Locus (Harlequin)
hh
Other Coat Traits

Other Coat Traits

Furnishings (RSPO2) LINKAGE
Likely unfurnished (no mustache, beard, and/or eyebrows) (II)
Coat Length (FGF5)
Likely short or mid-length coat (GG)
Shedding (MC5R)
Likely heavy/seasonal shedding (CC)
Hairlessness (FOXI3) LINKAGE
Very unlikely to be hairless (NN)
Oculocutaneous Albinism Type 2 (SLC45A2) LINKAGE
Likely not albino (NN)
Coat Texture (KRT71)
Likely straight coat (CC)
Other Body Features

Other Body Features

Muzzle Length (BMP3)
Likely medium or long muzzle (CC)
Tail Length (T)
Likely normal-length tail (CC)
Hind Dewclaws (LMBR1)
Likely to have hind dew claws (CT)
Blue Eye Color (ALX4) LINKAGE
Less likely to have blue eyes (NN)
Body Size

Body Size

Body Size (IGF1)
Smaller (II)
Body Size (IGFR1)
Smaller (AA)
Body Size (STC2)
Smaller (AA)
Body Size (GHR - E191K)
Smaller (AA)
Body Size (GHR - P177L)
Smaller (TT)
Performance

Performance

Altitude Adaptation (EPAS1)
Normal altitude tolerance (GG)
Appetite (POMC) LINKAGE
Normal food motivation (NN)

Through Nikki’s mitochondrial DNA we can trace her mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that her ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1c

Map

B1

Sunny Lion's In The Nyck of Thyme at A & A’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1c

Sunny Lion's In The Nyck of Thyme at A & A’s Haplotype

Part of the large B1 haplogroup, we have detected this haplotype in Mexico and Lebanon village dogs. Among the 12 breeds that we have spotted this haplotype in, it occurs most frequently in Border Collies, Australian Shepherd Dogs, and West Highland white Terriers.

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

The Paternal Haplotype reveals a dog’s deep ancestral lineage, stretching back thousands of years to the original domestication of dogs.

Are you looking for information on the breeds that Nikki inherited from her mom and dad? Check out her breed breakdown and family tree.

Paternal Haplotype is determined by looking at a dog’s Y-chromosome—but not all dogs have Y-chromosomes!

Why can’t we show Paternal Haplotype results for female dogs?

All dogs have two sex chromosomes. Female dogs have two X-chromosomes (XX) and male dogs have one X-chromosome and one Y-chromosome (XY). When having offspring, female (XX) dogs always pass an X-chromosome to their puppy. Male (XY) dogs can pass either an X or a Y-chromosome—if the puppy receives an X-chromosome from its father then it will be a female (XX) puppy and if it receives a Y-chromosome then it will be a male (XY) puppy. As you can see, Y-chromosomes are passed down from a male dog only to its male offspring.

Since Nikki is a female (XX) dog, she has no Y-chromosome for us to analyze and determine a paternal haplotype.