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“Mac”
DMD's Mac Peak

Poodle (Standard)

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Registration

AKC: PR20653805

Genetic Breed Result

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Poodle (Standard)

Poodle (Standard) Poodle (Standard)
Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.
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Genetic Stats

Wolfiness: 0.0 % LOW Learn More
Predicted Adult Weight: 60 lbs Learn More
Genetic Age: 18 human years Learn More

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Health

Traits

Maternal Haplotype

Paternal Haplotype

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Summary

0
AT RISK
0
CARRIER
166
CLEAR
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Clinical traits

These genetic traits are valuable to your veterinarian and can inform the clinical decisions and diagnoses they make.

Alanine Aminotransferase Activity result: Low Normal
This result helps your vet understand what your dog's baseline ALT activity is. The enzyme alanine aminotransferase, or ALT, is commonly used to evaluate liver health. Do…
DMD's Mac Peak has one copy of a mutation associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that DMD'…

Not At Risk

Good news! Mac did not test positive for any of the genetic diseases that Embark screens for.

It is still important to let your veterinarian know these results because they could help guide Mac’s diagnosis and treatment if he gets sick in the future.

Not A Carrier

Good news! Mac is not a carrier for any of the genetic diseases that Embark tests for.

Common Conditions

Good news! Mac tested clear for 7 genetic conditions that are common in his breed.
Condition List

Von Willebrand Disease Type I
(VWF)
Blood

Coagulopathies, disorders of blood clotting, can lead to symptoms such as easy bruising or bleeding. Dogs with coagulopathies are often at risk for excessive bleeding dur…

Congenital Macrothrombocytopenia
(TUBB1 Exon 1, Cavalier King Charles Spaniel Variant)
Blood

This is a benign disorder of platelet production that leads to abnormally large, sparse platelets. Affected dogs typically do not suffer any ill effects from the size or …

Progressive Retinal Atrophy - prcd
Progressive rod-cone degeneration (PRCD Exon 1)
Eyes

This retinal disease causes progressive, non-painful vision loss. The retina contains the cells, photoreceptors, that collect information about light: that is, they are t…

GM2 Gangliosidosis
(HEXB, Poodle Variant)
Multisystem

An early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young adults. These include partial or total visi…

Degenerative Myelopathy
(SOD1A)
Brain and Spinal Cord

A disease of mature dogs, this is a progressive degenerative disorder of the spinal cord that can cause muscle wasting and gait abnormalities. Affected dogs do not usuall…

Neonatal Encephalopathy with Seizures (NEWS)
(ATF2)
Brain and Spinal Cord

A neurologic disease of puppies, affected puppies are often smaller than their unaffected littermates and require intensive nursing care. Without this extra support, pupp…

Osteochondrodysplasia, Skeletal Dwarfism
(SLC13A1)
Skeletal

A form of skeletal dwarfism, this causes affected dogs to have abnormally short legs but a normal sized body due to abnormal fetal skeletal maturation. As a fetus, most o…

Other Conditions:
Clear of 159

Mac is clear of 159 other genetic diseases that Embark tests for.

Reports and Downloads

Veterinary Report For your veterinarian

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Traits

Maternal Haplotype

Paternal Haplotype

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Coat Color

A number of genes are known to affect coat color in dogs, and they all interact. In some cases, other genetic effects may also influence color and pattern.

Trait
Result
 
E Locus (Mask, Grizzle, Recessive Red)
Ee
K Locus (Dominant Black)
KBky
A Locus (Agouti, Sable)
ayat
D Locus (Dilute, Blue, Fawn)
DD
B Locus (Brown, Chocolate, Liver, Red, Dudley)
Bb

Other Embark dogs with these Coat Color genes:

Other Coat Traits

Furnishings, shedding and curls are all genetic! And they all interact, too. In fact, the combination of these genes explains the coat phenotypes of 90% of AKC registered dog breeds.

Trait
Result
 
Furnishings / Improper Coat (RSPO2)
FF
Long Haircoat (FGF5)
TT
Shedding (MC5R)
CC
Curly Coat (KRT71)
TT
Hairlessness (FOXI3)
LINKAGE
N/N
Oculocutaneous Albinism Type 2 - OCA2, Doberman Z Factor Albinism (SLC45A2)
LINKAGE
N/N

More information on coat type genetics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897713/figure/F3/

Other Embark dogs with these Coat Traits genes:

Other Body Features

Trait
Result
 
Brachycephaly (BMP3)
CC
Natural Bobtail (T)
CC
Hind Dewclaws (LMBR1)
CC
Blue Eye Color
LINKAGE
N/N

Body Size

Body size is a complex trait that is affected by both genetic and environmental variation. Our genetic analysis includes genes that, together, explain over 80% of the variation in dog body size. It does not account for runting or stunting; nor does it account for the interactions between various genes both known and unknown.

Trait
Result
 
Body Size - IGF1
NN
Body Size - IGF1R
GG
Body Size - STC2
TT
Body Size - GHR (E195K)
GG
Body Size - GHR (P177L)
CC

Other Embark dogs with these Body Size genes:

Performance

Trait
Result
 
Altitude Adaptation (EPAS1)
GG

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Health

Maternal Haplotype

Paternal Haplotype

Through Mac’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

B1

Haplotype

B1b

Map

B1

DMD's Mac Peak’s Haplogroup

B1 is the second most common maternal lineage in breeds of European or American origin. It is the female line of the majority of Golden Retrievers, Basset Hounds, and Shih Tzus, and about half of Beagles, Pekingese and Toy Poodles. This lineage is also somewhat common among village dogs that carry distinct ancestry from these breeds. We know this is a result of B1 dogs being common amongst the European dogs that their conquering owners brought around the world, because nowhere on earth is it a very common lineage in village dogs. It even enables us to trace the path of (human) colonization: Because most Bichons are B1 and Bichons are popular in Spanish culture, B1 is now fairly common among village dogs in Latin America.

B1b

DMD's Mac Peak’s Haplotype

Part of the large B1 haplogroup, we see this haplotype in village dogs across the world, including those from Central America, the Middle East, South Asia, and the French Polynesian Islands. Among the 31 breed dogs we see it in, we see it in Poodles, Otterhounds, and Labrador Retrievers. It is also our most commonly-sampled Golden Retriever haplotype!

Some other Embark dogs with this haplotype:

The B1 haplogroup can be found in village dogs like the Peruvian Village Dog, pictured above.

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Health

Traits

Paternal Haplotype

Through Mac’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1a

Haplotype

H1a.8

Map

A1a

DMD's Mac Peak’s Haplogroup

Some of the wolves that became the original dogs in Central Asia around 15,000 years ago came from this long and distinguished line of male dogs. After domestication, they followed their humans from Asia to Europe and then didn't stop there. They took root in Europe, eventually becoming the dogs that founded the Vizsla breed 1,000 years ago. The Vizsla is a Central European hunting dog, and all male Vizslas descend from this line. During the Age of Exploration, like their owners, these pooches went by the philosophy, "Have sail, will travel!" From the windy plains of Patagonia to the snug and homey towns of the American Midwest, the beaches of a Pacific paradise, and the broad expanse of the Australian outback, these dogs followed their masters to the outposts of empires. Whether through good fortune or superior genetics, dogs from the A1a lineage traveled the globe and took root across the world. Now you find village dogs from this line frolicking on Polynesian beaches, hanging out in villages across the Americas, and scavenging throughout Old World settlements. You can also find this "prince of patrilineages" in breeds as different as German Shepherds, Golden Retrievers, Pugs, Border Collies, Scottish Terriers, and Irish Wolfhounds. No male wolf line has been as successful as the A1a line!

H1a.8

DMD's Mac Peak’s Haplotype

Part of the large A1a haplogroup, this very common haplotype occurs in village dogs throughout the world (including southeast Asia, which is uncommon for A1a’s). Among the 25 breeds we see this haplotype in, it occurs most frequently in Labrador Retriever, Vizsla, and English Springer Spaniel.

Some other Embark dogs with this haplotype:

Dogs with A1a lineage travelled during European Colonial times.

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Health

Traits

Maternal Haplotype