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900164004022017

Mixed Ancestry

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Place of Birth

Bismarck, Arkansas, USA

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Registration

Continental Kennel Club (CKC):

Genetic Breed Result

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Border Collie

Border Collies are highly energetic and work-oriented herding dogs, whose stamina is matched by their intelligence and alertness. While they excel at the herding they were bred for, many Border Collies also enjoy flyball, obedience, and other canine sports. As long as they have a job to do and are physically and mentally stimulated, Border Collies can make excellent companions for the right owners.

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Poodle (Standard)

Known as the national dog breed of France, poodles were developed in Germany and are known for their loyalty and distinctive coat.

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Genetic Stats

Predicted Adult Weight

43 lbs

Genetic Age
20 human years

Based on the date of birth provided

DNA Breed Origins

Breed colors:
Border Collie
Poodle (Standard)

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Health Summary

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900164004022017 inherited one variant that you should learn more about.

And one variant that you should tell your vet about.

Collie Eye Anomaly

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900164004022017 inherited one copy of the variant we tested

What does this result mean?

This result should not impact 900164004022017’s health but it could have consequences for siblings or other related dogs if they inherited two copies of the variant. We recommend discussing this result with their owners or breeders if you are in contact.

Impact on Breeding

Your dog carries this variant and will pass it on to ~50% of his offspring.

What is Collie Eye Anomaly?

Named for its high prevalence in Collie dogs, Collie Eye Anomaly (CEA) is more correctly termed choroidal hypoplasia. The choroid anchors the retina to the underlying structures and supplies it with oxygen and nourishment. CEA is a developmental disease of the choroid.

ALT Activity

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900164004022017 inherited one copy of the variant we tested

Why is this important to your vet?

900164004022017 has one copy of a variant associated with reduced ALT activity as measured on veterinary blood chemistry panels. Please inform your veterinarian that 900164004022017 has this genotype, as ALT is often used as an indicator of liver health and 900164004022017 is likely to have a lower than average resting ALT activity. As such, an increase in 900164004022017’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT reference ranges.

What is ALT Activity?

Alanine aminotransferase (ALT) is a clinical tool that can be used by veterinarians to better monitor liver health. This result is not associated with liver disease. ALT is one of several values veterinarians measure on routine blood work to evaluate the liver. It is a naturally occurring enzyme located in liver cells that helps break down protein. When the liver is damaged or inflamed, ALT is released into the bloodstream.

Breed-Relevant Genetic Conditions

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Multiple Drug Sensitivity (ABCB1)

Identified in Border Collies

Von Willebrand Disease Type I, Type I vWD (VWF)

Identified in Standard Poodles

Trapped Neutrophil Syndrome, TNS (VPS13B)

Identified in Border Collies

Progressive Retinal Atrophy, prcd (PRCD Exon 1)

Identified in Standard Poodles

Goniodysgenesis and Glaucoma, Pectinate Ligament Dysplasia, PLD (OLFM3)

Identified in Border Collies

Primary Lens Luxation (ADAMTS17)

Identified in Border Collies

Neuronal Ceroid Lipofuscinosis 5, NCL 5 (CLN5 Exon 4 SNP, Border Collie Variant)

Identified in Border Collies

GM2 Gangliosidosis (HEXB, Poodle Variant)

Identified in Standard Poodles

Degenerative Myelopathy, DM (SOD1A)

Identified in Standard Poodles

Neonatal Encephalopathy with Seizures, NEWS (ATF2)

Identified in Standard Poodles

Sensory Neuropathy (FAM134B, Border Collie Variant)

Identified in Border Collies

Myotonia Congenita (CLCN1 Exon 23, Australian Cattle Dog Variant)

Identified in Border Collies

Cobalamin Malabsorption (CUBN Exon 53, Border Collie Variant)

Identified in Border Collies

Osteochondrodysplasia (SLC13A1, Poodle Variant)

Identified in Standard Poodles

Raine Syndrome (FAM20C)

Identified in Border Collies

Intervertebral Disc Disease (Type I) (FGF4 retrogene - CFA12)

Identified in Standard Poodles

Additional Genetic Conditions

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Explore the genetics behind your dog’s appearance and size.

Coat Color

Coat Color

Other Coat Traits

Other Coat Traits

Other Body Features

Other Body Features

Body Size

Body Size

Performance

Performance

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Through 900164004022017’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

C2

Haplotype

C40

Map

C2

900164004022017’s Haplogroup

C2 is a very old female lineage found more commonly among English Setters, English Bulldogs, and American Eskimo Dogs. We also see C2 in village dogs in South Asia. Rather than having a few characteristic breeds representing this lineage particularly well, it is present in a few uncommon individuals of many different breeds. Unlike some European breed lineages that have seen skyrocketing popularity along the path to the modern dogs we see today, C2 tends to reflect the deep history of man's best friend.

C40

900164004022017’s Haplotype

Part of the C2 haplogroup, this haplotype occurs most frequently in mixed breed dogs.

Some other Embark dogs with this haplotype:

You can often find his haplogroup in the lovable English Bulldog.

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Through 900164004022017’s Y-chromosome we can trace his father’s ancestry back to where dogs and people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below the map.

Haplogroup

A1b

Haplotype

Ha.44

Map

A1b

900164004022017’s Haplogroup

For most of dog history, this haplogroup was probably quite rare. However, a couple hundred years ago it seems to have found its way into a prized male guard dog in Europe who had many offspring, including the ancestors of many European guard breeds such as Doberman Pinchers, St. Bernards, and Great Danes. Despite being rare, many of the most imposing dogs on Earth have it; strangely, so do many Pomeranians! Perhaps this explains why some Poms are so tough, acting like they're ten times their actual size! This lineage is most commonly found in working dogs, in particular guard dogs. With origins in Europe, it spread widely across other regions as Europeans took their dogs across the world.

Ha.44

900164004022017’s Haplotype

Part of the A1b haplogroup, this haplotype occurs primarily in Poodles and Belgian Sheepdogs.

Some other Embark dogs with this haplotype:

Great Danes and Pomeranians have this in common!

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